NCT06494033
招募中
不适用
Prophylaxis Guided by Cytomegalovirus-specific T Cell Immunity to Prevent Cytomegalovirus Disease in Lung Transplant Recipients: a Single Center Prospective Study
概览
- 阶段
- 不适用
- 状态
- 招募中
- 入组人数
- 100
- 试验地点
- 1
- 主要终点
- Positive CMV Immunoglobulin (IgG) positive lung transplant
概览
简要总结
The purpose of this study is to evaluate the clinical outcomes of Cytomegalovirus (CMV) virus in the participants' body. Therefore, the study team will follow the participants' immunological response based on the Cytomegalovirus (CMV) virus testing.
研究设计
- 研究类型
- Observational
- 观察模型
- Cohort
- 时间视角
- Prospective
入排标准
- 年龄范围
- 18 Years 至 75 Years（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •Adult patients over 18 years of age
- •Lung transplant candidates with positive CMV IgG
- •Anticipated to receive a lung transplant (both double lung and single lung)
排除标准
- •Negative CMV IgG prior transplant
- •Pregnant or breastfeeding women
- •HIV infected patients
- •Combined organ (e.g., lung-heart, lung-kidney) transplant candidates
结局指标
主要结局
Positive CMV Immunoglobulin (IgG) positive lung transplant
时间窗: Up to 1 year
Positive CMV Immunoglobulin (IgG) measured by IU/ml
次要结局
- Graft Outcome status(Up to 1 year)
- Number of dead participants(Up to 1 year)
- Duration of CMV medication(Up to 1 year)
- Number of patients with CMV-positive results(Up to 1 year)
- Severity of CMV Disease(Up to 1 year)
- Severity of Torque Teno virus(Up to 1 year)
研究者
Yoichiro Natori
Associate Professor of Clinical
University of Miami
研究点 (1)
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