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Studying aerosol emission of the COVID-19 virus in healthcare settings

Not Applicable
Completed
Conditions
COVID-19 (SARS-CoV-2 infection)
Infections and Infestations
Registration Number
ISRCTN21447815
Lead Sponsor
orth Bristol NHS Trust
Brief Summary

2021 Preprint results in https://doi.org/10.1101/2021.01.29.21250552 non-peer-reviewed aerosol emission results in preprint (added 19/03/2021) 2021 Results article in https://pubmed.ncbi.nlm.nih.gov/34700360/ manual facemask ventilation quantitative evaluation (added 27/10/2021) 2021 Preprint results in https://doi.org/10.1101/2021.12.12.21267658 tracheal intubation and extubation sequences quantitative evaluation in preprint (added 16/12/2021)

Detailed Description

Not available

Recruitment & Eligibility

Status
Completed
Sex
All
Target Recruitment
600
Inclusion Criteria

Patients:
1. Undergoing procedure that is potentially aerosol-generating
2. Aged over 18
3. Have capacity

Healthy volunteers:
1. Have capacity to consent to the study
2. Aged over 18

Exclusion Criteria

Patients:
1. Unable to read/understand PIS (either printed version or via translator)
2. Unable to consent

Healthy volunteers:
1. Flu-like symptoms (fevers, temperature, new cough, sore throat, loss of smell, breathing difficulties) in the 48 hours prior to study enrolment
2. Clinical contraindication to the procedure being performed

Study & Design

Study Type
Observational
Study Design
Not specified
Primary Outcome Measures
NameTimeMethod
1. Distribution of aerosol produced during routine or simulated procedures measured using Aerodynamic Particle Sensors during the procedure, and for up to 10 minutes after<br>2. Distribution of aerosol produced during routine or simulated procedures measured using Optical Particle Sensors during the procedure, and for up to 10 minutes after
Secondary Outcome Measures
NameTimeMethod
Distribution of aerosol produced and dissemination measured with Aerodynamic and Optical Particle sensors across a clinical room during procedures and for up to 1 hour after
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