JPRN-jRCT2080223988招募中1 期
A Single Ascending Dose Study to Investigate the Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of LY3209590 in Japanese Patients with Type 2 Diabetes Mellitus
试验速览
- 阶段
- 1 期
- 状态
- 招募中
研究概览
简要总结
暂无简介。
研究设计
- 研究类型
- Interventional
入排标准
- 年龄范围
- >= 20age old 至 <= 70age old（—）
- 性别
- All
入选标准
- •Inclusion Criteria:
- •1. Have T2DM diagnosed at least 1 year
- •2. Have hemoglobin A1c (HbA1c) >=7.0% and <=10.0% with Fasting Plasma Glucose (FPG) of >=126 mg/dL, or HbA1c >=6.5% and <7.0% with FPG of >=144 mg/dL, at screening
- •3. Have a body weight of >=54 kg, and a body mass index of >18.5 and <=40.0 kg/m2 at screening
排除标准
- •Exclusion Criteria:
- •1. Have received a total daily dose of insulin >1.2 U/kg at screening
- •2. Have taken any glucose-lowering medications, other than basal insulin, metformin and dipeptidyl peptidase-IV inhibitor, in the past 3 months before screening
- •3. Have a history of multiple and/or severe allergies to drugs or foods, or a history of severe anaphylactic reaction.
- •4. Have a history of heart block, or a repeated demonstration of abnormality in the 12-lead ECG at screening, in the opinion of the investigator, increases the risks associated with participating in the study
研究者
相似试验
已完成
1 期
A Study of LY3537031 in Healthy ParticipantsJPRN-jRCT2031200242Wakayama Naohiko60
进行中（未招募）
不适用
Single-Dose, Dose Escalation Study to Assess the Safety, Tolerability, Pharmacokinetics and Bronchodilatory Effects of Glycopyrrolate Inhalation Solution (GIS) Using a High Efficiency Nebulizer in Patients with COPDChronic Obstructive Pulmonary Disease (COPD)MedDRA version: 9.1Level: LLTClassification code 10010952Term: COPDEUCTR2009-010821-38-GBElevation Pharmaceuticals, Inc12
已完成
不适用
A single ascending dose trial to investigate the safety, tolerability, pharmacokinetics, pharmacodynamics, and food effect of orally administered AS-0871 in healthy subjectsRheumatoid arthritisNL-OMON49497Carna Biosciences, Inc.16
已完成
不适用
A study in healthy males to assess the safety and tolerability of two different formulations of the study drug, (MSP-2017), administered intranasally.This study is for healthy volunteers. The intended use of the investigational product is to self-terminate acute episodes of paroxysmal supraventricular tachycardia (PSVT), a non-life threatening cardiac arrhythmia.Cardiovascular - Coronary heart diseaseACTRN12613000971730CPR Pharma Services48
已完成
不适用
A Phase 1 Multiple Dose Study to Investigate the Safety, Tolerability, Pharmacokinetics and Pharmacodynamics of IV SYNT001 in Healthy Volunteers.NL-OMON45830Syntimmune32