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Clinical Trials/NCT02767986
NCT02767986
Completed
Not Applicable

Where Culture Meets Genetics: Exploring Latinas' Causal Attributions of Breast and Colon Cancer and Mental Models of Disease Inheritance

National Human Genome Research Institute (NHGRI)1 site in 1 country22 target enrollmentMay 10, 2016

Overview

Phase
Not Applicable
Intervention
Not specified
Conditions
Colon Cancer
Sponsor
National Human Genome Research Institute (NHGRI)
Enrollment
22
Locations
1
Primary Endpoint
causal attributions of colon cancer
Status
Completed
Last Updated
last year

Overview

Brief Summary

Background:

Culture can affect the way a person thinks about illness. This can affect how they seek help for illness. It can also affect how they choose a treatment and follow it. This can lead to health disparities among certain groups of people. Breast and colon cancers are the most common cancers for Latinos. Even though they get these cancers at lower rates than other population groups, Latinos are more likely to be diagnosed with these cancers at advanced stages. Researchers want to study what Latina women immigrants believe causes breast and colon cancer and other factors they think play a role in disease. This understanding could lead to better interactions between Latinos and their doctors.

Objective:

To learn more about what Latina immigrants believe causes breast and colon cancer and other factors they think play a role in disease.

Eligibility:

Women ages 18 and older who:

Were born in Latin America

Speak Spanish

Have never had breast, ovarian, or colon cancer

Design:

Participants will be interviewed in person or over the phone. This will take up to an hour. The interview will be recorded. Participants will answer questions about:

Their family s cancer history

What they think causes breast and colon cancer

What they think plays a role in disease

...

Detailed Description

Research to understand the sources of health disparities has acknowledged that in addition to biomedical risk factors, culture plays an important role in differential health outcomes. Consequently, understanding cultural differences that may influence health behavior is key in working towards reducing these disparities. Causal attributions are a key component of individuals illness perceptions and thus impact health behaviors, which may present as health disparities at a population level. While research has explored non-Hispanic White women s causal attributions of breast cancer, less is known about Latina s beliefs about the causes of breast cancer, and little is known about causal attributions of colon cancer in any population. Understanding Latina s causal attributions of breast and colon cancer may provide insight into the determinants of cancer disparities in this population. Because a subset of both breast and colon cancers result from single gene mutations, which confer an increased risk of developing such cancers, understanding causal attributions in Latina populations is relevant to the field of genetics. This is especially true since Latinas have historically underutilized cancer genetic risk assessment counseling and testing services. As these services become a standard part of general healthcare provision, it will become increasingly important to understand ways in which different cultural groups interact with genetic information. One way this can be done is through investigating culturally informed mental models of disease risk and inheritance. This study seeks to describe causal attributions of breast and colon cancer and to explore mental models of disease inheritance among Latina immigrants . A qualitative exploratory design including interviews comprised of free-listing, ranking, and open-ended questions will be used. Participants will be recruited through the NIH Clinical Research Volunteer Program as well as using other resources within the Office of Participant Recruitment and from among individuals enrolled on other NIH Clinical Center protocols. First, we will describe Latina s causal attributions for these cancers. Next, we will use cultural consensus theory (CCT) to identify and describe common cultural models of causes of these cancers. Finally, we will explore Latina s mental models of disease inheritance using both free-listing and open-ended questions.

Registry
clinicaltrials.gov
Start Date
May 10, 2016
End Date
February 2, 2017
Last Updated
last year
Study Type
Observational
Sex
Female

Investigators

Eligibility Criteria

Inclusion Criteria

  • Not provided

Exclusion Criteria

  • Not provided

Outcomes

Primary Outcomes

causal attributions of colon cancer

Time Frame: baseline

participants' free-lists of colon cancer causes

mental models of inheritance

Time Frame: baseline

qualitative descriptions of women's understanding/thoughts about inheritance

causal attributions of breast cancer

Time Frame: baseline

participants' free-lists of breast cancer causes

Study Sites (1)

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