Fine and Gross Motor Function and Relationship With Muscle Tone in Older Adults With and Without Dementia
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 入组人数
- 122
- 试验地点
- 1
- 主要终点
- anteroposterior jerk
研究概览
简要总结
The purpose of this study was (1) to investigate changes in gait, balance, fine motor function, and muscle tone, and (2) to find out if there is a correlation between muscle tone/presence of paratonia and motor function (gross and fine) in mild and moderate dementia.Three groups of participants were included in the study: healthy elderly (n=60), participants with mild dementia (n=31) and participants with moderate dementia (n=31). Measurements of fine motor function, balance, gait, presence of paratonia and muscle tone measurements were performed.
研究设计
- 研究类型
- Interventional
- 分配方式
- Non Randomized
- 干预模型
- Parallel
- 主要目的
- Other
- 盲法
- None
入排标准
- 年龄范围
- 65 Years 至 —（Older Adult）
- 性别
- All
- 接受健康志愿者
- 是
入选标准
- •age >= 65 years
- •walk independently for at least 11 meters
- •HC: no cognitive deterioration, MiD: dementia, Global Deterioration Scale<5, MoD: dementia, Global Deterioration Scale 5 or 6
排除标准
- •recent (≤ 6 months) orthopedic surgery
研究组 & 干预措施
MiD
older adults with mild dementia
干预措施: Gait accelerometry (Other)
MiD
older adults with mild dementia
干预措施: balance accelerometry (Other)
HC
Healthy controls, i.e. older adults without cognitive impairment
干预措施: Gait accelerometry (Other)
HC
Healthy controls, i.e. older adults without cognitive impairment
干预措施: balance accelerometry (Other)
HC
Healthy controls, i.e. older adults without cognitive impairment
干预措施: Fine motor skill test (Other)
HC
Healthy controls, i.e. older adults without cognitive impairment
干预措施: Paratonia Assessment Instrument (PAI) (Diagnostic Test)
HC
Healthy controls, i.e. older adults without cognitive impairment
干预措施: myotonometric measurement of muscle tone (Other)
MiD
older adults with mild dementia
干预措施: Fine motor skill test (Other)
MiD
older adults with mild dementia
干预措施: Paratonia Assessment Instrument (PAI) (Diagnostic Test)
MiD
older adults with mild dementia
干预措施: myotonometric measurement of muscle tone (Other)
MoD
older adults with moderate dementia
干预措施: Gait accelerometry (Other)
MoD
older adults with moderate dementia
干预措施: balance accelerometry (Other)
MoD
older adults with moderate dementia
干预措施: Fine motor skill test (Other)
MoD
older adults with moderate dementia
干预措施: myotonometric measurement of muscle tone (Other)
结局指标
主要结局
anteroposterior jerk
时间窗: through study completion, an average of 3 years
balance smoothness and coordination, lower jerk values correspond with better smoothness of balance
walking speed
时间窗: through study completion, an average of 3 years
gait speed parameter
step regularity
时间窗: through study completion, an average of 3 years
gait parameter representing regularity, autocorrelation (method Moe-Nilssen 2004), value between 0 and 1, with 1 representing perfect regularity
Fine motor function
时间窗: through study completion, an average of 3 years
score on the Purdue pegboard test, maximal amount of (pairs of) pegs placed in 30 seconds (max. 25)
presence of paratonia
时间窗: through study completion, an average of 3 years
Paratonia Assessment Instrument, resistance against passive movements of the four limbs is evaluated (Hobbelen 2008)
mediolateral jerk
时间窗: through study completion, an average of 3 years
balance smoothness and coordination, lower jerk values correspond with better smoothness of balance
MyotonPRO measurement of muscle tone
时间窗: through study completion, an average of 3 years
MyotonPRO measurement
次要结局
- MyotonPRO measurement of mechanical stiffness(through study completion, an average of 3 years)
- MyotonPRO measurement of elasticity(through study completion, an average of 3 years)