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Clinical Trials/NCT03479567
NCT03479567
Completed
N/A

Fine and Gross Motor Function and Relationship With Muscle Tone in Older Adults With and Without Dementia

University Ghent1 site in 1 country122 target enrollmentJanuary 2015

Overview

Phase
N/A
Intervention
Not specified
Conditions
Dementia
Sponsor
University Ghent
Enrollment
122
Locations
1
Primary Endpoint
anteroposterior jerk
Status
Completed
Last Updated
2 years ago

Overview

Brief Summary

The purpose of this study was (1) to investigate changes in gait, balance, fine motor function, and muscle tone, and (2) to find out if there is a correlation between muscle tone/presence of paratonia and motor function (gross and fine) in mild and moderate dementia.Three groups of participants were included in the study: healthy elderly (n=60), participants with mild dementia (n=31) and participants with moderate dementia (n=31). Measurements of fine motor function, balance, gait, presence of paratonia and muscle tone measurements were performed.

Registry
clinicaltrials.gov
Start Date
January 2015
End Date
December 2017
Last Updated
2 years ago
Study Type
Interventional
Study Design
Parallel
Sex
All

Investigators

Responsible Party
Sponsor

Eligibility Criteria

Inclusion Criteria

  • age \>= 65 years
  • walk independently for at least 11 meters
  • HC: no cognitive deterioration, MiD: dementia, Global Deterioration Scale\<5, MoD: dementia, Global Deterioration Scale 5 or 6

Exclusion Criteria

  • recent (≤ 6 months) orthopedic surgery

Outcomes

Primary Outcomes

anteroposterior jerk

Time Frame: through study completion, an average of 3 years

balance smoothness and coordination, lower jerk values correspond with better smoothness of balance

walking speed

Time Frame: through study completion, an average of 3 years

gait speed parameter

step regularity

Time Frame: through study completion, an average of 3 years

gait parameter representing regularity, autocorrelation (method Moe-Nilssen 2004), value between 0 and 1, with 1 representing perfect regularity

Fine motor function

Time Frame: through study completion, an average of 3 years

score on the Purdue pegboard test, maximal amount of (pairs of) pegs placed in 30 seconds (max. 25)

presence of paratonia

Time Frame: through study completion, an average of 3 years

Paratonia Assessment Instrument, resistance against passive movements of the four limbs is evaluated (Hobbelen 2008)

mediolateral jerk

Time Frame: through study completion, an average of 3 years

balance smoothness and coordination, lower jerk values correspond with better smoothness of balance

MyotonPRO measurement of muscle tone

Time Frame: through study completion, an average of 3 years

MyotonPRO measurement

Secondary Outcomes

  • MyotonPRO measurement of mechanical stiffness(through study completion, an average of 3 years)
  • MyotonPRO measurement of elasticity(through study completion, an average of 3 years)

Study Sites (1)

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