Fine and Gross Motor Function and Relationship With Muscle Tone in Older Adults With and Without Dementia

Not Applicable

Completed

• Conditions: Paratonia; Gait; Muscle Tone; Fine Motor Function; Dementia; Balance

• Registration Number: NCT03479567
• Lead Sponsor: University Ghent

Brief Summary

The purpose of this study was (1) to investigate changes in gait, balance, fine motor function, and muscle tone, and (2) to find out if there is a correlation between muscle tone/presence of paratonia and motor function (gross and fine) in mild and moderate dementia.Three groups of participants were included in the study: healthy elderly (n=60), participants with mild dementia (n=31) and participants with moderate dementia (n=31). Measurements of fine motor function, balance, gait, presence of paratonia and muscle tone measurements were performed.

Detailed Description

Not available

Study Timeline

• Study Start: 2015-01
• Primary Completion: 2017-12
• Study Completion: 2017-12
• Study First Submitted: 2018-03-13
• Study First Submitted QC: 2018-03-20
• Study First Posted: 2018-03-27
• Status Verified: 2023-12
• Last Update Submitted: 2023-12-12
• Last Update Posted: 2023-12-18

Recruitment & Eligibility

• Status: COMPLETED
• Sex: All
• Target Recruitment: 122

Inclusion Criteria

• age >= 65 years
• walk independently for at least 11 meters
• HC: no cognitive deterioration, MiD: dementia, Global Deterioration Scale<5, MoD: dementia, Global Deterioration Scale 5 or 6

Exclusion Criteria

• recent (≤ 6 months) orthopedic surgery

Study & Design

• Study Type: INTERVENTIONAL
• Study Design: PARALLEL

Primary Outcome Measures

Name	Time	Method
walking speed	through study completion, an average of 3 years	gait speed parameter
anteroposterior jerk	through study completion, an average of 3 years	balance smoothness and coordination, lower jerk values correspond with better smoothness of balance
step regularity	through study completion, an average of 3 years	gait parameter representing regularity, autocorrelation (method Moe-Nilssen 2004), value between 0 and 1, with 1 representing perfect regularity
Fine motor function	through study completion, an average of 3 years	score on the Purdue pegboard test, maximal amount of (pairs of) pegs placed in 30 seconds (max. 25)
presence of paratonia	through study completion, an average of 3 years	Paratonia Assessment Instrument, resistance against passive movements of the four limbs is evaluated (Hobbelen 2008)
mediolateral jerk	through study completion, an average of 3 years	balance smoothness and coordination, lower jerk values correspond with better smoothness of balance
MyotonPRO measurement of muscle tone	through study completion, an average of 3 years	MyotonPRO measurement

Secondary Outcome Measures

Name	Time	Method
MyotonPRO measurement of mechanical stiffness	through study completion, an average of 3 years	MyotonPRO measurement
MyotonPRO measurement of elasticity	through study completion, an average of 3 years	MyotonPRO measurement

Trial Locations

Locations (1)

Vakgroep Revaki - Ghent University; 🇧🇪 Ghent, Belgium