Comparative Evaluation of Ceraseal, MTA Fillapex and AH Plus sealer on postoperative pain after single visit root canal treatment - A Randomized controlled Clinical trial

Single-visit root canal treatment offers numerous benefits that significantly enhance patient experience and clinical outcomes. One of the most compelling advantages is the substantial reduction in treatment time, allowing patients to complete their procedure in one appointment and minimizing disruption to their daily lives. Additionally, this approach can alleviate dental anxiety, as it reduces the stress associated with multiple appointments, including the need for repeated anaesthetic injections and rubber dam placements. Importantly, single-visit treatment significantly lowers the risk of root canal contamination and bacterial regrowth, which can occur with prolonged treatment intervals. By maintaining continuity, clinicians can better understand canal anatomy, tooth length, and other vital parameters, enhancing treatment precision while avoiding complications such as inter-visit leakage and loss of temporary seals. However, it is essential to acknowledge certain limitations of single-visit procedures. The absence of diagnostic controls available in multi-visit treatments may hinder the ability to culture samples for assessing the effectiveness of biomechanical preparation or to evaluate tissue responses post-treatment. Moreover, in the event of a flare-up or complications, emergency interventions can become more complex, requiring procedures such as artificial fistulation or the removal of fillings. Ultimately, while single-visit root canal treatment provides significant advantages, both patients and clinicians must weigh these benefits against potential limitations to ensure informed decision-making for optimal dental health outcomes.

This randomized controlled trial aims to assess postoperative pain following single-visit root canal treatment in mandibular first molars, comparing the efficacy of three endodontic sealers: Ceraseal, MTA Fillapex, and AH Plus. Recognizing that pain perception is a complex and subjective experience influenced by numerous physical and psychological factors, this study will employ the Visual Analog Scale (VAS) for pain measurement. The VAS, a 100 mm horizontal line anchored by descriptive terms at each end, will be used to quantify patients’ pain levels. Participants will be instructed to mark their perceived pain at specified intervals: 6 hours, 12 hours, 24 hours, 48 hours, 3 days, and 7 days post-treatment. This methodology aims to provide a robust comparison of postoperative pain associated with the different sealers under investigation.