ISRCTN47438148已完成未知
Renoprotection of Optimal Antiproteinuric Doses of benazepril and losartan in chronic renal insufficiency: long-term analysis
ational Natural Science Foundation of China0 个研究点目标入组 360 人开始时间: 2006年9月4日最近更新:
试验速览
- 阶段
- 未知
- 状态
- 已完成
- 发起方
- 入组人数
- 360
研究概览
简要总结
2007 results in http://www.ncbi.nlm.nih.gov/pubmed/17494885
研究设计
- 研究类型
- Interventional
入排标准
- 性别
- All
入选标准
- •1. Serum creatinine concentration of 1.5 to 5.0 mg per deciliter (133 to 442 µmol/L)
- •2. Creatinine clearance of 20 to 70 ml per minute per 1.73 m^2, with variations of less than 30 percent in the three months before screening evaluation
- •3. Nondiabetic renal disease
- •4. Persistent heavier proteinuria (defined by urinary protein excretion of more than 1.0 g per day for three or more months without evidence of urinary tract infection or overt heart failure [a New York Heart Association class of III or IV])
排除标准
- •1. Immediate need for dialysis
- •2. Treatment with corticosteroids, non steroidal anti-inflammatory drugs, or immunosuppressive drugs
- •3. Hyper-or hypokalemia (serum potassium concentration 5.6 mmol per litre or more or 3.5 mmol per litre or less)
- •4. Renovascular disease
- •5. Myocardial infarction or cerebrovascular accident in the year preceding the trial
- •6. Connective-tissue disease and obstructive uropathy
研究者
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