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Clinical Trials/NCT05770154
NCT05770154
Completed
Not Applicable

Ankle Isokinetic Strength and Balance Assessment in Diabetic Patients With and Without Peripheral Neuropathy at Different Angular Velocities

Cairo University1 site in 1 country100 target enrollmentMarch 15, 2023
ConditionsDiabetes

Overview

Phase
Not Applicable
Intervention
Not specified
Conditions
Diabetes
Sponsor
Cairo University
Enrollment
100
Locations
1
Primary Endpoint
Peak torque
Status
Completed
Last Updated
last year

Overview

Brief Summary

Diabetic polyneuropathy (DPN) is a type of nerve damage that can occur in diabetics. It can cause weakness and a loss of sensation, particularly in the legs and feet. This can have an impact on muscle strength and balance, making walking more difficult and increasing the risk of falling. Evaluating ankle muscular strength and balance using quantitative and standardised tools is critical for patients with and without DPN as well as determining how much DPN affects ankle muscle strength and balance.

Detailed Description

Diabetic Peripheral Neuropathy (DPN) can affect ankle muscle strength and increase the risk of falling. This occurs due to nerve damage that impairs muscle function and reduces sensitivity in the feet, leading to difficulty maintaining balance and coordination. Risk factors for DPN-related falls include poor glycemic control, the duration of diabetes, age, and other comorbidities such as peripheral vascular disease. It is important for individuals with diabetes to regularly monitor and manage their DPN to prevent falls and maintain overall health. So, conducting this study to measure ankle muscle strength through isokinetic testing and dynamic balance through the Biodex balance system will help researchers quantify the extent of DPN's impact on these aspects. This study can provide a valuable predictor and assessment tool for determining the severity of neuropathy in diabetic patients. The results of this study could also help identify those at a higher risk for falls and diabetic foot complications. This information can aid healthcare providers in developing tailored interventions to improve muscle strength and balance and reduce the risk of falls in individuals with diabetes and DPN.

Registry
clinicaltrials.gov
Start Date
March 15, 2023
End Date
December 30, 2024
Last Updated
last year
Study Type
Observational
Sex
All

Investigators

Responsible Party
Principal Investigator
Principal Investigator

Doaa Ayoub Elimy Mohammed

Lecturer of physical therapy for basic science department., faculty of physical Therapy

Cairo University

Eligibility Criteria

Inclusion Criteria

  • Patients aged from 40 to 55 years for both gender.
  • Patients with diabetes for more than 5 years.
  • Diabetic polyneuropathy was diagnosed by a neurologist.
  • Their BMI from 18 to 24.9 kg/m
  • The study population must be willing to participate in the study.

Exclusion Criteria

  • Patients with marked deformities of the lower limbs, foot ulcers and Charcot foot.
  • .Patients with any other neurological or orthopedic diseases that may affect balance.
  • Patients with marked weakness or drop foot.
  • Patients with amputation, mental deficits, liver or renal diseases.
  • patients who had a previous surgical history (within 6 months) were also excluded prior to the baseline assessment

Outcomes

Primary Outcomes

Peak torque

Time Frame: Through study completion, an average of 6 months.

Isokinetic dynamometer will be used for measuring ankle dorsi and planter flexors peak torque at different angular velocities.

Secondary Outcomes

  • Power(Through study completion, an average of 6 months.)
  • Work(Through study completion, an average of 6 months.)
  • Dynamic balance(Through study completion, an average of 6 months.)

Study Sites (1)

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