Investigating the Efficacy of Cognitive Behavioral Therapy in Patients With Substance Use Disorder and Comorbid ADHD. A Randomized Controlled Trial With Cognitive Behavioral Therapy
Trial Snapshot
- Phase
- Not Applicable
- Status
- Completed
- Sponsor
- Enrollment
- 184
- Locations
- 1
- Primary Endpoint
- self reported ADHD symptoms
Study Overview
Brief Summary
The purpose of this study is to determine if cognitive behavioral therapy is effective in treating ADHD symptoms in patients with substance use disorders and comorbid ADHD.
Detailed Description
Attention Deficit Hyperactivity Disorder(ADHD) is an important comorbid condition in patients with substance use disorders (SUD). The prevalence of ADHD in patients with SUD is estimated 23%, and ADHD is associated with an untoward prognosis of SUD. However, adequate treatment programs for patients with ADHD and SUD are not available. Results of medication trials for patients with ADHD and SUD are disappointing, and cognitive behavioral therapy (CBT) has not yet been investigated in this population. In patients with ADHD without comorbid SUD, the results of CBT in randomized trials are positive. The purpose of this study is to investigate if CBT is effective in treating ADHD symptoms in patients with ADHD and SUD.
Study Design
- Study Type
- Interventional
- Allocation
- Randomized
- Intervention Model
- Parallel
- Primary Purpose
- Treatment
- Masking
- None
Eligibility Criteria
- Ages
- 18 Years to 60 Years (Adult)
- Sex
- All
- Accepts Healthy Volunteers
- No
Inclusion Criteria
- •substance use disorder
- •able to comply with study activities
Exclusion Criteria
- •severe neurological or psychiatric diseases (for example Parkinson, dementia, psychosis, bipolar depression) which require medication
- •unable to read or write Dutch language
Outcomes
Primary Outcomes
self reported ADHD symptoms
Time Frame: 6 months
Dutch self report list of ADHD symptoms by Kooij and Buitelaar
Secondary Outcomes
- TIC-P(6 months)
- Stroop task(6 months)
- Time Line Follow Back method(6 months)
- EQ-5(6 months)
- Beck Anxiety Inventory(6 months)
- urine checks(6 months)
- BART task(6 months)
- Beck depression inventory(6 months)
- Tower of London task(6 months)