Strengthening hip muscles to improve walking distance in people with Charcot-Marie-Tooth disease

Completed

• Conditions: Charcot-Marie-Tooth disease; Nervous System Diseases; Hereditary and idiopathic neuropathy

• Registration Number: ISRCTN87551289
• Lead Sponsor: niversity College London Hospitals NHS Foundation Trust (UK)

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Study Start: 2009-05-12
• Last Update Posted: 17 October 2016

Recruitment & Eligibility

• Status: Completed
• Sex: All
• Target Recruitment: 32

Inclusion Criteria

People will be recruited provided all of the following criteria are satisfied:
1. Clinical diagnosis of Charcot-Marie-Tooth disease (CMT)
2. Aged 18 to 70 years, either sex
3. Able to walk for 50 m with or without a walking aid or orthotic devices
4. Signed informed participant consent

Exclusion Criteria

People will be excluded from the study if one or more of the following criteria apply:
1. Presence of other significant neurological disorders (such as multiple sclerosis, cerebrovascular diseases, movement disorders), or major comorbidities (e.g., definite cognitive impairment, psychiatric disease, heart or lung failure, orthopaedic or rheumatological disorders)
2. Limb surgery during the six months prior to screening (or planned before final assessment)
3. Severe congenital hip dysplasia associated with CMT
4. Aged over 70 or under 18 years
5. Women of child-bearing age only if they are pregnant at the inclusion into the study or plan to become pregnant during the study (people agreeing not to become pregnant during the study must take appropriate contraceptive methods - contraceptive pill, intrauterine device, barrier methods)

Study & Design

• Study Type: Interventional
• Study Design: Not specified