Biomarkers for outcome at school age in preterm born childre

Completed

• Conditions: brain damage; White matter injury; 10028920; 10009841; 10010335

• Registration Number: NL-OMON50419
• Lead Sponsor: eonatologie, Wilhelmina Kinderziekenhuis

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Study Completion: 2023-01-16
• Last Update Posted: 23 April 2024

Recruitment & Eligibility

• Status: Completed
• Sex: Not specified
• Target Recruitment: 118

Inclusion Criteria

Born between January 2007 and December 2012.
Gestational age <28 weeks.
Age at assessment: 7-11 years.

Exclusion Criteria

Major chromosomal and/or congenital anomalies.
Inability to comply with the study procedures.

Study & Design

• Study Type: Observational invasive
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
<p>The main study parameters are intelligence quotient and GFAP (a<br /><br>neuroinflammatory marker).</p><br>

Secondary Outcome Measures

Name	Time	Method
<p>The secondary study parameters are mismatch negativity (derived from EEG) and<br /><br>presence of behavioral disorders and virtual reality parameters indicating<br /><br>level of cognitive skills in a more dynamic and interactive simulated<br /><br>environment.</p><br>