ACTRN12617001418369招募中4 期
The safety and pharmacokinetics of metformin in heart failure
St Vincent's Hospital Sydney0 个研究点目标入组 50 人开始时间: 2017年10月9日最近更新:
适应症
试验速览
- 阶段
- 4 期
- 状态
- 招募中
- 发起方
- 入组人数
- 50
研究概览
简要总结
暂无简介。
研究设计
- 研究类型
- Interventional
- 分配方式
- Non-randomised trial
- 主要目的
- Treatment
- 盲法
- Open (masking not used)
入排标准
- 年龄范围
- 18 Years 至 o limit（—）
- 性别
- All
入选标准
- •Study B & C - Patients with heart failure (NYHA Grade I-III, Preserved or Reduced Ejection Fraction)
- •Patients not currently taking metformin
- •Study A - Patients with heart failure (NYHA Grade I-III, Preserved or Reduced Ejection Fraction)
- •Patients currently taking metformin
排除标准
- •Patients who are currently on metformin
- •Patients who have type II diabetes mellitus (Study B & C Only)
- •Women lactating, pregnant or of childbearing potential who are not willing to avoid becoming pregnant during the study.
- •Patients with a history of a psychological illness or condition such as to interfere with the patient's ability to understand the requirements of the study.
- •Patients with a history of lactic acidosis.
- •Patients with grade IV heart failure
- •Patients with chronic kidney disease ( creatinine clearance < 30 ml/min)
研究者
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