跳至主要内容
临床试验/NCT01947257
NCT01947257Unknown不适用

Is There a Correlation Between the Pulmonary Artery Pressure and the Acceleration of the Flow in the Pulmonary Artery Evaluated by Transesophageal Echocardiography (TOE) ?

Assistance Publique Hopitaux De Marseille2 个研究点 分布在 1 个国家目标入组 50 人开始时间: 2013年9月最近更新:
适应症
干预措施

试验速览

阶段
不适用
入组人数
50
试验地点
2
主要终点
measure of the pulmonary artery pressure

研究概览

简要总结

The measure of the pulmonary artery pressure (PAP) is a very useful index in intensive care to estimate right ventricular after load. The reference technique for this measure is the right catheterism which is an invasive technique. It is possible to estimate the pulmonary artery pressure by using transthoracic echocardiography (TTE) which allows, using the continuous Doppler, the measure of maximum speed of tricuspid regurgitation (TRvmax). The measure of the TRvmax can however be difficult for intensive care patients with little echogenicity or impossible for those having no tricuspid leak. The evaluation of the tricuspid regurgitation is also particularly difficult using TOE. To avoid these drawbacks, one can use the analysis of the pulmonary ejection in the pulmonary artery (PAAT) with TOE. However, the data of the literature are controversial on this method and it was not validated in mechanically ventilated intensive care patients.

The aim of this work is to compare three methods of measure of the PAP: the measure TRVMAX (by means of the tricuspid leak) by transthoracic echocardiography, the measure of the TAAP by transesophageal ultrasound and the direct measure of the pulmonary pressures by right catheterization, in ventilated patients already monitored with a catheter in the right cavities for usual indications in intensive care (ARDS, shock). We shall analyze then the correlation between the TRVmax, the TAAP and the pressures measured by the right catheterism which serves as reference technique.

研究设计

研究类型
Interventional
分配方式
Na
干预模型
Single Group
主要目的
Basic Science
盲法
None

入排标准

年龄范围
18 Years 至 —(Adult, Older Adult)
性别
All
接受健康志愿者

入选标准

  • Patients aged over 18 years
  • Admitted to intensive care
  • Mechanically ventilated and sedated
  • Carrying a right catheterization
  • Making a ETO indicated by the medical team or doctor in charge of the patient

排除标准

  • Patients under 18 years
  • expectant mother
  • Patients without health insurance
  • Refusal to close

研究组 & 干预措施

ventilated patients

Other

干预措施: the measure TRVMAX (Other)

ventilated patients

Other

干预措施: the measure of the pulmonary artery (Other)

ventilated patients

Other

干预措施: the direct measure of the pulmonary pressures (Other)

结局指标

主要结局

measure of the pulmonary artery pressure

时间窗: 12 months

次要结局

未报告次要终点

研究者

申办方类型
Other
责任方
Sponsor

研究点 (2)

Loading locations...

相似试验