Study of the Reversibility of Vigilance Dysfunction at 6 Months of Continuous Positive Airways Pressure (CPAP) in Patients With Obstructive Sleep Apnea/Hypopnea Syndrome (OSAHS)

Not Applicable

Completed

• Conditions: Vigilance Dysfunction
• Interventions: Diagnostic Test: tests of attentional performance

• Registration Number: NCT03344263
• Lead Sponsor: Poitiers University Hospital

Brief Summary

It is a monocentric prospective pilot study in Poitiers University Hospital, specifically analyzing the vigilance disorders in the Obstructive Sleep Apnea Hypopnea Syndrome (OSAHS) and their reversibility after 6 months of Continuous positive airways pressure (CPAP).

All subjects were administered a test of vigilance (Test of Attentional Performance) both before and after the 6 months of CPAP.

The main objective is the study of the reversibility of alertness disorders on the number of omissions in the subtest visual vigilance of the TAP ( (Test of Attentional Performance) at 6 months of CPAP in the OSAHS in patients with a memory complaint.

Detailed Description

Not available

Study Timeline

• Study First Submitted: 2017-11-13
• Study First Submitted QC: 2017-11-13
• Study Start: 2017-11-17
• Study First Posted: 2017-11-17
• Primary Completion: 2021-02-09
• Study Completion: 2021-02-09
• Status Verified: 2021-11
• Last Update Submitted: 2021-11-26
• Last Update Posted: 2021-11-29

Recruitment & Eligibility

• Status: COMPLETED
• Sex: All
• Target Recruitment: 23

Inclusion Criteria

• Patients aged 20-70 years

• Memory disorders without memory problems in episodic memory

• Presence of polysomnography of a obstructive sleep apnea/hypopnea syndrome (OSAHS) requiring Continuous positive airways pressure

  • Moderate OSAHS (Apnea Hypopnea Index ≥ 15 / hour with arousals ≥ 10)
  • Severe OSAHS (Apnea Hypopnea Index ≥ 30 / h)

Exclusion Criteria

• Age <20 years or ≥ 70 years
• Neurodegenerative disease (Alzheimer's disease, Parkinson's disease)
• Dysthyroidism
• Severe depression, schizophrenia, bipolar disorder
• Treatment with an effect on cognition: hypnotics, sedative
• Chronic Obstructive Pulmonary Disease
• Chronic alcoholism, other addictions
• Contraindications to Magnetic Resonance Imaging
• Refusal of equipment

Study & Design

• Study Type: INTERVENTIONAL
• Study Design: SINGLE_GROUP

Arm && Interventions

Group	Intervention	Description
tests of attentional performance	tests of attentional performance	-

Primary Outcome Measures

Name	Time	Method
Study of the reversibility of vigilance disorders on the number of omissions in the subtest visual vigilance of the TAP	After 6 months of continuous positive airways pressure in the OSAHS patient	Reversibility of vigilance disorders on the number of omissions in the subtest visual vigilance of the TAP

Trial Locations

Locations (1)

service de neurologie CHU DE POITIERS; 🇫🇷 Poitiers, France