Effects of probiotics on lipid profile, glycemic index, oxidative stress and inflammatory markers in patients with diabetes type 2

Phase 3

Conditions: Non-insulin-dependent diabetes mellitus
Type 2 Diabetes.

Registration Number: IRCT2016071127879N2

Lead Sponsor: Bushehr University of Medical Sciences

Brief Summary: Not available

Detailed Description: Not available

Recruitment & Eligibility

Status: Complete

Sex: All

Target Recruitment: 40

Inclusion Criteria

Inclusion Criteria: Patients with diabetes type 2 are enrolled with FBS=126 mgr/dl; less than 15 years of medical history; the age range is 25 to 65 years; the elective subjects, next drugs prescribed by physicians, should be controlled the status of glucose and lipid levels and during the study could use these drugs without changing in the prior dosage.

Exclusion Criteria

Patients with diabetes type 2 that used alternative treatments like hormone therapy or supplemental vitamins; also those used tobacco and alcohol; patients with chronic kidney disease; liver, lung, chronic or acute inflammatory disease (especially acute pancreatic inflammation and Endocarditis); heart valve disease; short bowel syndrome; allergies; people with low immune system ability (autoimmune); pregnant or lactating women.

Study & Design

Study Type: interventional

Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
ipid Profile (Tg,Total Chol, LDL-C, HDL-C). Timepoint: Before and After Intervention. Method of measurement: Autoanalyzer.;Serum Glucose. Timepoint: Before and after Intervention. Method of measurement: Autoanalyzer.;Serum Insulin Levels. Timepoint: Before and After Intervention. Method of measurement: ELISA.;Hs-CRP. Timepoint: Before and after intervention. Method of measurement: ELISA.;IL-6. Timepoint: Before and After Intervention. Method of measurement: Autoanalyzer.;Malodialdehyde (MDA). Timepoint: Before and after Intervention. Method of measurement: Specterophotometery.

Secondary Outcome Measures