Effect of Dexmedetomidine vs Midazolam on the microcirculation of septic patients who are mechanically ventilated
Not Applicable
Completed
- Conditions
- Circulatory SystemsepsisAnaesthesia
- Registration Number
- PACTR202112845314910
- Lead Sponsor
- Mostafa Mohamed Atef Mohamed
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Complete
- Sex
- All
- Target Recruitment
- 128
Inclusion Criteria
Both males and females • Age more than 21 years old • Patients having sepsis requiring sedation for mechanical ventilation, according to the third international consensus definitions for sepsis and septic shock (sepsis-3).
Exclusion Criteria
Pregnant or breast-feeding women • Age < 21 years old • Allergy to any of the drugs used in the study • 2nd or 3rd degree Heart block • Systolic blood pressure < 90 • Patient with EF < 30% example (Heart failure, MI) • HR < 50 bpm • Child B or C cirrhotic liver disease • Documented Acute coronary syndromes • Presence of Intra-cardiac shunts • The need to use positive inotropic drugs for circulatory support
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method
- Secondary Outcome Measures
Name Time Method