Dexamethasone for the Prevention of Recurrent Laryngeal Nerve Palsy

Completed

• Conditions: Malignant Neoplasm of Thyroid; Benign Neoplasm of Thyroid Gland

• Registration Number: NCT01690806
• Lead Sponsor: Università degli Studi dell'Aquila

Brief Summary

Recurrent laryngeal nerve dysfunction and hypoparathyroidism are well-recognized important complications of thyroid surgery. The duration of convalescence, after non complicated thyroid operation, may depend on several factors of which pain and fatigue are the most important. Nausea and vomiting occur mainly on the day of operation. Glucocorticoids are well known for their analgesic, anti-inflammatory, immune modulating and antiemetic effects. The investigators therefore undertook the present study to investigate whether preoperative dexamethasone could improve surgical outcome in patients undergoing thyroid surgery.

Detailed Description

Not available

Study Timeline

• Study Start: 2008-01
• Status Verified: 2011-08
• Primary Completion: 2012-01
• Study Completion: 2012-03
• Study First Submitted: 2012-09-19
• Study First Submitted QC: 2012-09-21
• Study First Posted: 2012-09-24
• Last Update Submitted: 2012-09-25
• Last Update Posted: 2012-09-26

Recruitment & Eligibility

• Status: COMPLETED
• Sex: All
• Target Recruitment: 328

Inclusion Criteria

• patients undergoing thyroid surgery

Exclusion Criteria

• ASA physical class III or IV
• age > 75 years
• pregnancy

Study & Design

• Study Type: OBSERVATIONAL
• Study Design: Not specified

Trial Locations

Locations (1)

ospedale San Salvatore-Reparto di Chirurgia Generale Universitaria; 🇮🇹 L'Aquila, AQ, Italy