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Clinical Trials/NCT01690806
NCT01690806
Completed
Not Applicable

Dexamethasone for the Prevention of Recurrent Laryngeal Nerve Palsy (and Not Only) After Thyroid Surgery. A Randomized Double-blind Placebo-controlled Trial.

Università degli Studi dell'Aquila1 site in 1 country328 target enrollmentJanuary 2008

Overview

Phase
Not Applicable
Intervention
Not specified
Conditions
Benign Neoplasm of Thyroid Gland
Sponsor
Università degli Studi dell'Aquila
Enrollment
328
Locations
1
Status
Completed
Last Updated
13 years ago

Overview

Brief Summary

Recurrent laryngeal nerve dysfunction and hypoparathyroidism are well-recognized important complications of thyroid surgery. The duration of convalescence, after non complicated thyroid operation, may depend on several factors of which pain and fatigue are the most important. Nausea and vomiting occur mainly on the day of operation. Glucocorticoids are well known for their analgesic, anti-inflammatory, immune modulating and antiemetic effects. The investigators therefore undertook the present study to investigate whether preoperative dexamethasone could improve surgical outcome in patients undergoing thyroid surgery.

Registry
clinicaltrials.gov
Start Date
January 2008
End Date
March 2012
Last Updated
13 years ago
Study Type
Observational
Sex
All

Investigators

Sponsor
Università degli Studi dell'Aquila
Responsible Party
Principal Investigator
Principal Investigator

CECILIA Emanuela Marina

M.D.

Università degli Studi dell'Aquila

Eligibility Criteria

Inclusion Criteria

  • patients undergoing thyroid surgery

Exclusion Criteria

  • ASA physical class III or IV
  • age \> 75 years
  • pregnancy

Outcomes

Primary Outcomes

Not specified

Study Sites (1)

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