NCT03033927
进行中（未招募）
不适用
Circulating Tumor Cell and Tumor Tissue Models for Predicting Effective Pancreatic Cancer Response
概览
- 阶段
- 不适用
- 干预措施
- CTC isolocation and analysis
- 疾病 / 适应症
- Pancreatic Cancer
- 发起方
- Memorial Sloan Kettering Cancer Center
- 入组人数
- 74
- 试验地点
- 8
- 主要终点
- Progression Free Survival
- 状态
- 进行中（未招募）
- 最后更新
- 5天前
概览
简要总结
The purpose of this phase II study is to develop a test to predict response of pancreatic cancer to different chemotherapy regimens.
研究者
入排标准
入选标准
- •Histological or cytological diagnosis of pancreatic adenocarcinoma, confirmed at MSKCC, AJCC stage IV disease at time of enrollment.
- •Patient planning to receive treatment with FOLFIRINOX or gem/nab-P chemotherapy, with or without investigational agents.
- •Prior surgery, chemotherapy and/or radiation therapy for AJCC Stage I-III pancreatic adenocarcinoma is permitted.
- •ECOG performance status 0-
- •A minimum age of 18 years old.
排除标准
- •Prior chemotherapy for AJCC stage IV pancreatic adenocarcinoma
- •Known to be HIV positive on antiretroviral therapy
- •Prior organ allograft
- •Any medical or psychiatric condition that may interfere with the ability to comply with protocol procedures
研究组 & 干预措施
Participants with Stage IV Pancreatic Cancer
干预措施: CTC isolocation and analysis
结局指标
主要结局
Progression Free Survival
时间窗: 36 months
in patients receiving frontline therapy predicted to be effective versus ineffective based on CTC PGx analysis
研究点 (8)
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