NCT03033927进行中（未招募）不适用
Circulating Tumor Cell and Tumor Tissue Models for Predicting Effective Pancreatic Cancer Response
适应症
干预措施
试验速览
- 阶段
- 不适用
- 状态
- 进行中（未招募）
- 入组人数
- 74
- 试验地点
- 8
- 主要终点
- Progression Free Survival
研究概览
简要总结
The purpose of this phase II study is to develop a test to predict response of pancreatic cancer to different chemotherapy regimens.
研究设计
- 研究类型
- Observational
- 观察模型
- Cohort
- 时间视角
- Prospective
入排标准
- 年龄范围
- 18 Years 至 —（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •Histological or cytological diagnosis of pancreatic adenocarcinoma, confirmed at MSKCC, AJCC stage IV disease at time of enrollment.
- •Patient planning to receive treatment with FOLFIRINOX or gem/nab-P chemotherapy, with or without investigational agents.
- •Prior surgery, chemotherapy and/or radiation therapy for AJCC Stage I-III pancreatic adenocarcinoma is permitted.
- •ECOG performance status 0-
- •A minimum age of 18 years old.
排除标准
- •Prior chemotherapy for AJCC stage IV pancreatic adenocarcinoma
- •Known to be HIV positive on antiretroviral therapy
- •Prior organ allograft
- •Any medical or psychiatric condition that may interfere with the ability to comply with protocol procedures
研究组 & 干预措施
Participants with Stage IV Pancreatic Cancer
干预措施: CTC isolocation and analysis (Diagnostic Test)
结局指标
主要结局
Progression Free Survival
时间窗: 36 months
in patients receiving frontline therapy predicted to be effective versus ineffective based on CTC PGx analysis
次要结局
未报告次要终点
研究者
研究点 (8)
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