Changes in bone and surrounding soft tissue structure, metabolism, and vascularisation in Patient with periprosthetic joint infection of the knee and hip
Recruiting
- Conditions
- T84.5Infection and inflammatory reaction due to internal joint prosthesis
- Registration Number
- DRKS00022515
- Lead Sponsor
- Charité Campus Mitte
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Recruiting
- Sex
- All
- Target Recruitment
- 60
Inclusion Criteria
Periprosthetic joint infection of the knee or hip
Exclusion Criteria
HIV Hepatitis C, Osteoporosis, No proven periprosthetic joint infection
Study & Design
- Study Type
- observational
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method In this study, inflammatory markers in bone and bone marrow are evaluated for elevation in patients with periprosthetic infection compared to the control group.
- Secondary Outcome Measures
Name Time Method In a secondary analysis, markers relevant for bone metabolism are examined in the obtained samples. In addition, a morphological evaluation of the effect on bone metabolism is performed by micro-CT examinations.