the Effect of Gut Microbiota on the Prognosis of Sepsis
试验速览
- 阶段
- 不适用
- 发起方
- 入组人数
- 30
- 主要终点
- Discharged from ICU
研究概览
简要总结
Sepsis is a life-threatening condition that arises when the body's response to infection injures its own tissues and organs. Common signs and symptoms include fever, increased heart rate, increased breathing rate, and confusion. Clinically, sepsis patients with diarrhea often result in a bad prognosis. Gut microbiota consists of a complex community of microorganisms that live in the digestive tracts of animals. The gut microbiota comprises the largest and most diverse reservoir of mutualistic microorganisms associated with animals. The aims of this study is to determin the effect of gut microbiota on the prognosis of Sepsis, by using 16s pyrosequencing, comparing the blood culture result.
研究设计
- 研究类型
- Observational
- 观察模型
- Case Control
- 时间视角
- Prospective
入排标准
- 年龄范围
- 18 Years 至 65 Years（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •Subjects diagnosed with sepsis
- •18 years to 65 years of age
排除标准
- •patients had complications such as acute cerebral infarction or acute myocardial infarction
- •The use of antibiotics, pro-prebiotics within 3 months
- •<18 years or >65 years
- •History of intestinal surgery
- •patients withdraw from this study
结局指标
主要结局
Discharged from ICU
时间窗: 7 days
次要结局
未报告次要终点
研究者
Deng Li
Ph.D. student
Jinan University Guangzhou