Efficacy Determination of Anti-wrinkle of A.G.E LOCK SERUM

Phase 1

Completed

• Conditions: Healthy Thai female subjects aged between 35-60 years; Anti-wrinkle

• Registration Number: TCTR20211215005
• Lead Sponsor: Thai-China Flavours and Fragrances, Co., Ltd.

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Study Completion: 2020-10-09
• Study Start: 2021-12-15
• Last Update Posted: 19 August 2024

Recruitment & Eligibility

• Status: Completed
• Sex: Female
• Target Recruitment: 33

Inclusion Criteria

1. Women between 35 and 60 years of age
2. All skin types (normal, dry, oily and combination skin)
3. Having clearly visible wrinkle at eye corner (crow's feet) or forehead
4. Having experience using a counter brand facial skin care
5. Willing to participate in the study after being informed objective, methodology, risk and benefit of the study
6. Be able to read, communicate and write Thai language
7. Willing to stop using commercially available skin smoothing, moisturizer, and anti-wrinkle products
8. Willing to sign the consent form after being explained and provided all
information related to potential impact of the study (volunteers can ask any information about this study except the confidential business information of product)

Exclusion Criteria

1. Having underlying disease and continuous taking medicine
2. Having history of eczema or psoriasis within 6 months before enrollment in this study
3. Having history of major operation within 1 year
4. Having history of skin cancer within 1 year
5. Having wound and scar around the study-evaluating face area
6. Applying any medicines for treatment facial skin diseases
7. Having history of using steroid, antibiotic, non-steroidal anti-inflammatory or antihistamine within 3 days before enrollment in this study
8. Having history of using topical medicine on face within 3 weeks before
enrollment in this study
9. Having allergic history to mangosteen, pomegranate, tomato, or carrot
10. Having allergic history to any ingredient in commercially available anti-wrinkle products
11. Pregnancy or lactation
12. Having history of smoking at least 1 cigarette/day
13. Having history of consuming at least 1 glass/day or 250 milliliters
14. Using or having history of substance abuse
15. Having history of participating in other clinical study within 3 months before enrollment in this study

Study & Design

• Study Type: Interventional
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Facial roughness and wrinkles 8 weeks measuring by Primos lite,Skin moisture 8 weeks measuring by Corneometer,Skin elasticity 8 weeks Measuring by Cutometer

Secondary Outcome Measures

Name	Time	Method
/A N/A N/A