The effect of Matricaria chamomilla L. on insulin resistance, inflammatory status and other related indices in patients with non-alcoholic fatty liver

Fasa University of Medical Sciences0 个研究点目标入组 44 人开始时间: 待定最近更新: 2019年8月26日

试验速览

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•sign the consent form
•age between 25-65 years
•BMI between 22-35
•Diagnosis of fatty liver and steatohepatitis with: A- serum level of Alanine Transaminease (ALT) More than one and a half times the highest normal limit(66/5000This means that more than 45 men and women more than or equal to 29 units per liter)Also, the amount of aspartate transaminase (AST) In both sexes is greater than 30 units per liter(According to the latest definition of ALT and abnormal AST in men and women). B- Diagnosis of fatty liver (moderate to high) in liver ultrasound.
•The patient have not to consume lipid regulating drugs for four weeks
•The patient have not to consume some drugs like silybin, ursodeoxycholic acid, Polyene Phosphatidylcholine, vitamin E and Medicinal herbs with blood lipid regulation effect and hepatoprotective effect from four weeks bfore entering to the study.

•pregnancy and lactation
•Liver failure (acute or chronic)
•Liver diseases such as autoimmune hepatitis, viral hepatitis B and C (active or inactive), Wilson's disease and etc.
•Hypo and hyperthyroidism
•Renal failure (creatinine above 1.5 mg / dL)
•Any malignancy (treated or not)
•Taking warfarin
•Addiction and alcohol consumption
•Taking contraceptives, ouroso-doxycyclic acid, glucocorticoid, statins, probiotics, vitamin E over the past three months
•Chamomile allergy history

发起方

Fasa University of Medical Sciences