Effect of moringa oleifera leaves on the blood glucose, blood pressure, lipid profile and haematological parameters of type 2 diabetics in a rural Nigerian community.
- Conditions
- Nutritional, Metabolic, Endocrine
- Registration Number
- PACTR202005626842621
- Lead Sponsor
- Ifeoma Christiana Afiaenyi
- Brief Summary
There was no significant (p > 0.05) difference in the waist circumference and waist hip ratio in all the groups after the feeding trial. There was no significant (p > 0.05) difference in the fasting blood glucose in all the groups after the feeding trial. Groups 3 (experimental group that consumed 40 g of Moringa oleifera leaves per day) and 4 (experimental group that consumed 60 g of Moringa oleifera leaves per day) had a significant (p < 0.05) decrease in their mean systolic pressure after the feeding trial. No significant (p > 0.05) difference was seen in the mean diastolic pressure and mean total cholesterol of the subjects after the feeding trial. There was a significant (p < 0.05) increase in the mean triglyceride level of the subjects in group 3. A significant (p < 0.05) reduction in low density lipoprotein was seen in group 2 (experimental group that consumed 20 g of Moringa oleifera per day) subjects. Group 3 subjects had significant (p < 0.05) increase in their mean very low density lipoprotein after the feeding trial. There was a significant (p < 0.05) increase in the mean high density lipoprotein in groups 1, 2 and 4. Significant (p < 0.05) reduction in the mean haemoglobin level, packed cell volume and white blood cell count was seen only in group 4 subjects. Significant changes observed in the parameters assessed were not dose dependent.
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Complete
- Sex
- All
- Target Recruitment
- 30
Type 2 diabetics aged 40 years and above.
Type 2 diabetics with no obvious complications such as foot ulcer, blindness and stroke.
Type 2 diabetics who were neither pregnant nor breastfeeding.
Type 2 diabetics who were not obese.
Type 2 diabetics who consented to partake in the study.
Type 2 diabetics who were below 40 years of age.
Type 2 diabetes with such complications such as foot ulcer, blindness and stroke.
Type 2 diabetics who were either pregnant or breastfeeding.
Type 2 diabetics who were obese.
Type 2 diabetics who did not give their consent to partake in the study.
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method
- Secondary Outcome Measures
Name Time Method