PUMA Paediatric early warning systems: Utility and Mortality Avoidance

Not Applicable

Completed

• Conditions: Topic: Children; Subtopic: All Diagnoses; Disease: All Diseases; Not Applicable

• Registration Number: ISRCTN94228292
• Lead Sponsor: Cardiff University

Brief Summary

2018 Protocol article in https://www.ncbi.nlm.nih.gov/pubmed/30045717 protocol 2019 Other publications in https://pubmed.ncbi.nlm.nih.gov/31727645/ hermeneutic systematic literature review and model development (added 20/10/2021) 2019 Other publications in https://pubmed.ncbi.nlm.nih.gov/31061010/ systematic review (added 20/10/2021)

Detailed Description

Not available

Study Timeline

• Results First Posted: 1900-01-01
• Study Start: 2015-08-18
• Study Completion: 2018-11-05
• Last Update Posted: 1 November 2021

Recruitment & Eligibility

• Status: Completed
• Sex: All
• Target Recruitment: 66

Inclusion Criteria

1. All children admitted to the four participating hospital's inpatient units general hospital wards (excluding high dependency and intensive care units)
2. The parents of some of these children
3. The healthcare professionals looking after some of these children

Exclusion Criteria

1. Preterm infants (<37 weeks gestation)
2. Adult patients >18 years of age
3. Patients not admitted to the hospital (e.g., those only seen in AED and discharged)
4. Patients admitted directly to PICU or HDU
5. Temporary or agency staff working in these departments

Study & Design

• Study Type: Observational
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
<br> The primary outcome measure is the monthly collected rate of mortality and the following critical events:<br> 1. Unplanned admission to Paediatric Intensive Care (PICU) or Paediatric High Dependency Unit (PHDU)<br> 2. Cardiac arrest<br> 3. Respiratory arrest<br> 4. Medical emergencies requiring immediate assistance (arrest calls who were not respiratory or cardiac arrests)<br> 5. Referrals for PICU review (in tertiary centres) or PICU retrieval (DGHs)<br> 6. The Critical Deterioration (CD) metric<br>

Secondary Outcome Measures

Name	Time	Method
<br> The secondary outcome measures are the monthly rates of each of the following critical events in each hospital:<br> 1. Mortality<br> 2. Unplanned admission to PICU or PHDU<br> 3. Cardiac arrest<br> 4. Respiratory arrest<br> 5. Medical emergencies requiring immediate assistance<br> 6. Referrals for PICU review (in tertiary centres) or PICU retrieval (DGHs)<br> 7. CD metric<br> 8. PIM3<br>