Influence of drug containing ginger extract on arthritic pain and gastropathy in patients with osteoarthritis

Completed

• Conditions: Osteoarthritis, NSAID-induced gastropathy; Musculoskeletal Diseases; Osteoarthritis

• Registration Number: ISRCTN48110500
• Lead Sponsor: Central Scientific Research Institute of Gastroenterology (Russia)

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Study Start: 2010-11-26
• Last Update Posted: 13 January 2015

Recruitment & Eligibility

• Status: Completed
• Sex: All
• Target Recruitment: 40

Inclusion Criteria

1. Aged over 18 years, either sex
2. Osteoarthritis (OA) pain syndrome availability of more than 40 mm according to Visual Analogue Scale (VAS)
3. Requiring anti-inflammatory therapy assignment
4. NSAID-gastropathy or dyspepsia development from NSAID therapy in anamnesis
5. Informed patient consent to administer the preparation
6. Compliance with the listed research protocol

Exclusion Criteria

1. Ulcer presence during upper gastrointestinal (GI) endoscopy and more than 5 stomach mucosa and/or duodenum erosions, and/or erosive oesophagitis
2. High risk of cardiological complications, arterial hypertension, cardiac insufficiency greater than II degree, myocardial infarction or apoplectic attack in anamnesis during the previous 3 years, chronic kidney disease, liver insufficiency, bronchial asthma, subcompensated or decompensated diabetes mellitus, oncological diseases
3. NSAID administration, aspirin in anti-aggregant doses, glucocorticosteroids
4. Pregnancy

Study & Design

• Study Type: Interventional
• Study Design: Not specified