Evaluation of the occurrence, effect and side effects oFcyclophosfamid and rituximab in the tratment of children with NEPHROTIC SYNDROM resistance to STEROID that referred to Hazrate Massumeh hospital .
Phase 2
- Conditions
- ephrotic syndrome resistance to steroide.Nephrotic syndrome with other morphologic changes
- Registration Number
- IRCT20170527034146N2
- Lead Sponsor
- Ghoum University of Medical Sciences
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Complete
- Sex
- All
- Target Recruitment
- 102
Inclusion Criteria
?All patient whit nephrotic syndrome resistance to steroid whit age 1-18 yr
Exclusion Criteria
All patient who do not have steroid-resistant Nephrotic Syndrome for example patient with steroids depended syndrome.
All patient who did not accept treatment
All patient who died
All patient who did not follow up
Study & Design
- Study Type
- interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method The frequency of relapse of the disease before and after taking the cyclofosfamide and ritoximab. Timepoint: Weekly. Method of measurement: Urin analysis of proteine.;Dosage of the prednisolon before and after taking the medication. Timepoint: weekly. Method of measurement: check liste.
- Secondary Outcome Measures
Name Time Method umber of relapses after receiving rutioxime and cyclolophosphamide. Timepoint: weekly. Method of measurement: Urinalysis. Patient's disease.;Dosage of Steroids after receiving medication. Timepoint: weekly. Method of measurement: check liste.