Trial of Montelukast for Treatment of Acute Bronchiolitis
- Registration Number
- NCT00863317
- Lead Sponsor
- Medical College of Wisconsin
- Brief Summary
The primary rationale for this study is to evaluate the effect of once daily montelukast on duration of acute illness in infants with first-time bronchiolitis.
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- COMPLETED
- Sex
- All
- Target Recruitment
- 141
Inclusion Criteria
- Male or female infants aged 3 to 12 months of age
- Diagnosis by emergency physician of bronchiolitis
Exclusion Criteria
- Any previous episode, as determined by a physician, of wheezing, bronchiolitis or asthma
- Any history of previous bronchodilator use prior to this illness
- Treatment with corticosteroids in the 14 days prior to the current illness
- Immunosuppression
- Immunodeficiency
- Caregiver does not speak English
- Diagnosis by the treating ED physician of croup
- Diagnosis by the treating ED physician of pneumonia
- Caregiver does not have access to a telephone
Study & Design
- Study Type
- INTERVENTIONAL
- Study Design
- PARALLEL
- Arm && Interventions
Group Intervention Description Placebo sucrose Sucrose granules PO QD for 14 days montelukast sodium montelukast sodium 4mg granules PO QD for 14 days
- Primary Outcome Measures
Name Time Method Duration of Cough up to 4 weeks
- Secondary Outcome Measures
Name Time Method
Trial Locations
- Locations (1)
Children's Hospital of Wisconsin
🇺🇸Milwaukee, Wisconsin, United States