To study the use of inflammatory markers to predict bad outcomes in babies who donot cry at birth
Not Applicable
Completed
- Conditions
- Health Condition 1: null- Perinatal asphyxia
- Registration Number
- CTRI/2013/10/004102
- Lead Sponsor
- JIPMER intramural research fund
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Completed
- Sex
- Not specified
- Target Recruitment
- 100
Inclusion Criteria
Cases include inborn babies with
1.Gestational age >=37 weeks
2.Evidence of encephalopathy (Sarnatâ??s staging)
3.Umbilical cord arterial blood pH <=7 and base deficit >=12 mmol/L)
4.Any two of the following criteria:
i.APGAR<=6 at 10 min
ii.Evidence of foetal distress
iii.Assisted ventilation for at least 10 min after birth
iv.Evidence of any organ dysfunction
v.History of acute perinatal event like intrapartum foetal distress, cord prolapse, placental abruption, uterine rupture.
Exclusion Criteria
1.Gestational age less than 37 weeks or > 42 weeks.
2.Evidence of obvious congenital malformations.
3.Major birth trauma.
4.Death of newborn within 72 hours.
5.Newborns born to mothers with systemic illness like diabetes, hypertension.
Study & Design
- Study Type
- Observational
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method eurodevelopmental sequelaeTimepoint: 6 months
- Secondary Outcome Measures
Name Time Method severity of asphyxiaTimepoint: 28 days