MedPath

Caregiver Burden and Wellbeing in Relatives of Intensive Care Unit Patients

Completed
Conditions
Social Responsibility
Registration Number
NCT02712541
Lead Sponsor
Karolinska University Hospital
Brief Summary

The purpose of this study is to determine whether there is an association between adverse physical and/or psychological outcome in ICU survivors and the caregiver burden for their relatives.

We hypothesize that relatives to ICU survivors with an incomplete physical and/or psychological recovery three months after ICU stay report a higher caregiver burden.

Detailed Description

This is a sub-study to the multicenter "PROGRESS study". Details of the PROGRESS study have been described elsewhere. Briefly, an observational study including 600-1000 adult ICU patients from ten European hospitals will be followed up during three months to identify potential risk factors for physical and psychological problems.

The sub-study is conducted in four Swedish hospitals (Karolinska University Hospital Solna, Södersjukhuset, Stockholm, Örebro University Hospital and Akademiska University Hospital in Uppsala). Relatives to patients included in the PROGRESS study, who give informed consent to participate are consecutively included in the study.

Consenting participants (relatives) will be approached after inclusion of the patient and asked to estimate their own health related quality of life (HRQOL) 2 weeks prior to the time point for patient ICU admission through a HRQOL questionnaire. This self-reported HRQOL data will be used as proxy for baseline data. Three months after ICU discharge, relatives to ICU survivors will receive the following questionnaires by postal mail; Caregiver Burden Index, HRQOL questionnaire, a questionnaire screening for symptoms of anxiety and depression and a questionnaire screening for symptoms of posttraumatic stress.

The relatives will also be asked to state the number of working days lost due to caretaking of the ICU survivor.

ICU survivors' physical and psychological outcome, assessed with BI, SF-36, PTSS-14 and HADS three months after ICU discharge, obtained in the main PROGRESS study, will be compared with relatives' reported caregiver burden.

Secondary outcomes are associations between caregiver burden and reported health-related quality of life between baseline and 3 months after ICU discharge, frequency of symptoms of anxiety, depression and posttraumatic stress 3 months post ICU discharge and number of working days lost because of their relative's critical illness.

Recruitment & Eligibility

Status
COMPLETED
Sex
All
Target Recruitment
75
Inclusion Criteria
  1. Relatives are considered eligible if they are a) partner to the patient b) adult children, siblings, parents or close friend that share household with the ICU survivor
Exclusion Criteria
  1. Non-Swedish-speaking
  2. Overt or documented cognitive impairment

Study & Design

Study Type
OBSERVATIONAL
Study Design
Not specified
Primary Outcome Measures
NameTimeMethod
Caregiver burden Index scoreThree months after patients' discharge from the ICU

Score compared between nearest of kin to patients with good or poor physical or psychological outcome (obtained in the main PROGRESS-ICU Study), three months after ICU discharge

Secondary Outcome Measures
NameTimeMethod
Short Form-36Three months after patients' ICU discharge

Relation between Caregiver burden Index scores and mental component score in SF-36

Hospital Anxiety and Depression ScaleThree months post ICU discharge

Relation between outcomes in patients and scores in nearest of kin

Posttraumatic stress symptoms Inventory - 14Three months post ICU discharge

Relation between patients outcome and nearest of kin scores

Trial Locations

Locations (4)

Örebro Universitetssjukhus

🇸🇪

Örebro, Sweden

Dept of Anesthesiology, Surgical Services and Intensive Care Medicine, Karolinska University Hospital

🇸🇪

Stockholm, Sweden

Stockholm South Hospital

🇸🇪

Stockholm, Sweden

Dept of Anesthesia and Intensive Care, Uppsala Akademiska

🇸🇪

Uppsala, Sweden

© Copyright 2025. All Rights Reserved by MedPath