A multicenter, open-label, randomized controlled trial to assess the efficacy and safety of appropriate target values for lipid management in patients who have mild to moderate stenosis lesions with high-risk plaques in coronary arteries

Not Applicable

• Conditions: Conditions having mild to moderate stenosis lesions with high-risk plaques in coronary arteries, but not yet developing ischemic heart disease

• Registration Number: JPRN-UMIN000031136
• Lead Sponsor: ational Hospital Organization Kure Medical Center

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Results First Posted: 1900-01-01
• Study Start: 2018-03-01
• Study Completion: 2023-03-31
• Last Update Posted: 17 October 2023

Recruitment & Eligibility

• Status: Complete: follow-up continuing
• Sex: All
• Target Recruitment: 95

Inclusion Criteria

Not provided

Exclusion Criteria

1)With a significant stenosis of the coronary artery which is an indication for revascularization 2)Having a history of myocardial infarction 3)Having a history of coronary artery revascularization (PCI or CABG) 4)Whose LDL-C value already satisfies the secondary prevention criteria in JAS Guideline for Prevention of Atherosclerotic Cardiovascular Diseases at the time of registration 5)Diagnosed with familial hypercholesterolemia-homozygote 6)With poorly controlled diabetes whose HbA1c value is 10% or more 7)With BMI of less than 17 kg/m2 8)With chronic kidney disease whose eGFR value is 30 mL/min/1.73 m2 or less 9)Having a history of complications suspected to be related to the contrast medium 10)With thyroid disease requiring treatment 11)Confirmed bronchial asthma, multiple myeloma, macroglobulinemia, tetany, or pheochromocytoma 12)Having a history of side effects caused by taking statins 13)In poor compliance with medication due to dementia 14)Judged to be inappropriate for participation in this study by the principal investigator/sub-investigators

Study & Design

• Study Type: Interventional
• Study Design: Not specified