Extended trough level measurement with extended release formulation of tacrolimus

Recruiting

• Conditions: renal transplantation; 10038430

• Registration Number: NL-OMON34374
• Lead Sponsor: niversitair Medisch Centrum Sint Radboud

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Last Update Posted: 6 May 2024

Recruitment & Eligibility

• Status: Recruiting
• Sex: Not specified
• Target Recruitment: 24

Inclusion Criteria

1. Recipient of a renal graft
2. Age: 18 years or older
3. Informed consent
4. At least 2 months after renal transplantation
5. Treatment with tacrolimus OD
6. Tacrolimus trough levels within the target range (5-10 ug/l) at two subsequent occasions.

Exclusion Criteria

1. Severe diarrhea (> 3 stools per day)
2. Change in tacrolimus dosage within one week prior to inclusion

Study & Design

• Study Type: Observational invasive
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
<p>The difference between trough levels measured at 24 hours and at 32 hours after<br /><br>taking of tacrolimus OD.</p><br>

Secondary Outcome Measures

Name	Time	Method
<p>The extent of correlation between these two measurements</p><br>