Short-term Effects of Lumbar Spine Manipulation Versus Pharmacological Therapy in Young Women With Primary Dysmenorrhea: a Randomized Controlled Trial.
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 发起方
- 入组人数
- 42
- 试验地点
- 2
- 主要终点
- Pain intensity
研究概览
简要总结
Many treatments like acupuncture, manipulative therapy and pharmacological therapy have been proposed to alleviate symptoms associated with dysmenorrhea. However, no study has previously compared lumbar spine manipulation to pharmacological therapy in the treatment of primary dysmenorrhea.
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Parallel
- 主要目的
- Treatment
- 盲法
- Single (Outcomes Assessor)
入排标准
- 年龄范围
- 18 Years 至 65 Years（Adult, Older Adult）
- 性别
- Female
- 接受健康志愿者
- 否
入选标准
- •Presented with persistent primary dysmenorrhea lasting for three or more consecutive menstrual periods
- •Presented menstrual cycles no longer than 35 days
排除标准
- •Presented any other gynecological pathologies
- •Systemic diseases
- •Previous surgical interventions for gynecological complaints
- •Depression
- •Were receiving any other treatment for primary dysmenorrhea.
研究组 & 干预措施
Lumbar spine manipulation
Application of lumbar spine manipulation by a physical therapist.
干预措施: Lumbar spine manipulation (Other)
Lumbar spine manipulation plus pharmacological therapy
Application of lumbar spine manipulation by a physical therapist along with pharmacological therapy.
干预措施: Lumbar spine manipulation (Other)
Lumbar spine manipulation plus pharmacological therapy
Application of lumbar spine manipulation by a physical therapist along with pharmacological therapy.
干预措施: Hyoscine and Ibuprofen (Drug)
Pharmacological therapy
Application of pharmacological therapy
干预措施: Hyoscine and Ibuprofen (Drug)
结局指标
主要结局
Pain intensity
时间窗: Change from baseline at 3 days
Pain intensity measured with a visual analogue scale
次要结局
- Pressure pain threshold measured in tibialis malleolus(Change from baseline at 3 days)
- Low-back related disability(Change from baseline at 1 month)
- Pressure pain threshold measured in peroneal malleolus(Change from baseline at 3 days)
- Anxiety and depression(Change from baseline at 1 month)
研究者
Prof. Dr. Daniel Pecos Martín
Doctor
University of Alcala