Short-term Effects of Lumbar Spine Manipulation Versus Pharmacological Therapy in Young Women With Primary Dysmenorrhea: a Randomized Controlled Trial.
Overview
- Phase
- Not Applicable
- Intervention
- Lumbar spine manipulation
- Conditions
- Women With Primary Dysmenorrhea
- Sponsor
- University of Alcala
- Enrollment
- 42
- Locations
- 2
- Primary Endpoint
- Pain intensity
- Status
- Completed
- Last Updated
- 3 years ago
Overview
Brief Summary
Many treatments like acupuncture, manipulative therapy and pharmacological therapy have been proposed to alleviate symptoms associated with dysmenorrhea. However, no study has previously compared lumbar spine manipulation to pharmacological therapy in the treatment of primary dysmenorrhea.
Investigators
Prof. Dr. Daniel Pecos Martín
Doctor
University of Alcala
Eligibility Criteria
Inclusion Criteria
- •Presented with persistent primary dysmenorrhea lasting for three or more consecutive menstrual periods
- •Presented menstrual cycles no longer than 35 days
Exclusion Criteria
- •Presented any other gynecological pathologies
- •Systemic diseases
- •Previous surgical interventions for gynecological complaints
- •Depression
- •Were receiving any other treatment for primary dysmenorrhea.
Arms & Interventions
Lumbar spine manipulation
Application of lumbar spine manipulation by a physical therapist.
Intervention: Lumbar spine manipulation
Lumbar spine manipulation plus pharmacological therapy
Application of lumbar spine manipulation by a physical therapist along with pharmacological therapy.
Intervention: Lumbar spine manipulation
Lumbar spine manipulation plus pharmacological therapy
Application of lumbar spine manipulation by a physical therapist along with pharmacological therapy.
Intervention: Hyoscine and Ibuprofen
Pharmacological therapy
Application of pharmacological therapy
Intervention: Hyoscine and Ibuprofen
Outcomes
Primary Outcomes
Pain intensity
Time Frame: Change from baseline at 3 days
Pain intensity measured with a visual analogue scale
Secondary Outcomes
- Pressure pain threshold measured in tibialis malleolus(Change from baseline at 3 days)
- Low-back related disability(Change from baseline at 1 month)
- Pressure pain threshold measured in peroneal malleolus(Change from baseline at 3 days)
- Anxiety and depression(Change from baseline at 1 month)