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Clinical Trials/NCT03801486
NCT03801486
Completed
Not Applicable

The Effects of Incorporating Sprouted and Non-sprouted Chickpea Flour in Pasta Products Analyzed in Vivo Flow-mediated Dilation

Montclair State University0 sites34 target enrollmentMarch 2, 2016

Overview

Phase
Not Applicable
Intervention
Not specified
Conditions
Endothelial Dysfunction
Sponsor
Montclair State University
Enrollment
34
Primary Endpoint
Post-digestion flow mediated dilation
Status
Completed
Last Updated
2 years ago

Overview

Brief Summary

The investigators examined the effects on post-digestion brachial artery flow mediated dilation (FMD) and in vitro antioxidant capacity of 40% semolina flour replacement with sprouted chickpea flour.

Detailed Description

The purpose of the current study was to examine in-vitro and in-vivo effects of replacing 40% of semolina flour with sprouted chickpea flour for the use in pasta. Antioxidant capacity in-vitro was measured by Trolox Equivalent Antioxidant Capacity. Brachial artery flow-mediated dilation, a test of in-vivo endothelial function, was performed for assessment of effects on post-digestion endothelial function. The investigators hypothesized that FMD would be higher after consuming 40% of semolina flour with sprouted chickpea flour pasta vs. 100% of semolina flour pasta.

Registry
clinicaltrials.gov
Start Date
March 2, 2016
End Date
May 1, 2017
Last Updated
2 years ago
Study Type
Observational
Sex
All

Investigators

Responsible Party
Sponsor

Eligibility Criteria

Inclusion Criteria

  • healthy adult

Exclusion Criteria

  • have diabetes mellitus, kidney disease, a history of cancer, cardiac issues, pulmonary disease, history of a stroke, obesity (for most people this means a body mass index greater than 30), or any life threatening chronic conditions.
  • food allergies relevant to wheat, gluten, chickpea, and pasta sauce.
  • are currently being treated for infectious mononucleosis, hepatitis, pneumonia, or other infectious diseases.
  • are unable or unwilling to refrain from recreational drug (marijuana, cocaine, etc.) or alcohol use during the 24 hours prior to your exercise session.
  • use nicotine products, or non-contraceptive hormonal therapy (birth control is okay).
  • are pregnant or trying to become pregnant.

Outcomes

Primary Outcomes

Post-digestion flow mediated dilation

Time Frame: Two hours following meal

Post meal

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