NCT03629132Unknown不适用
Platelet-rich Plasma(PRP) Prevents Recurrence of Intrauterine Adhesions
Yanhong Deng0 个研究点目标入组 60 人开始时间: 2018年8月15日最近更新:
适应症
干预措施
试验速览
- 阶段
- 不适用
- 发起方
- 入组人数
- 60
- 主要终点
- AFS score
研究概览
简要总结
Effect of platelet-rich plasma (PRP) on uterine scar fibrosis, endometrial receptivity and pregnancy outcome in patients with severe intrauterine adhesions
详细描述
- Inclusion criteria: patients with intrauterine adhesions (AFS score >9 points); age 21 to 40 years old, with fertility requirements.
- Study design:prospective, randomized controlled cohort study, patients with intrauterine adhesions were randomized into two groups, the control group and the intervention group (intraoperative and postoperative 1 week postoperative PRP). The surgical procedures and postoperative medication regimens were the same.
- Compare the biochemical pregnancy rate, clinical pregnancy rate, abortion rate and live birth rate after hysteroscopic resection in PRP group and control group, and explore the effect of PRP on pregnancy outcome after intrauterine adhesion.
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Single Group
- 主要目的
- Prevention
- 盲法
- None
入排标准
- 年龄范围
- 20 Years 至 37 Years（Adult）
- 性别
- Female
- 接受健康志愿者
- 否
入选标准
- •Patients with intrauterine adhesions (AFS score >9 points); age 21 to 40 years old, with fertility requirements -
排除标准
- •Endometrial tuberculosis, endometrial polyps, uterine submucosal fibroids, endometrial hyperplasia, endometrial malignant lesions, premature ovarian failure, chromosomal abnormalities
研究组 & 干预措施
Gel
Sham Comparator
Self-crosslinking sodium hyaluronate gel
干预措施: gel (Procedure)
PRP
Experimental
Platelet-rich plasma
干预措施: Platelet-rich plasma (Procedure)
结局指标
主要结局
AFS score
时间窗: 1 year
AFS score
次要结局
未报告次要终点
研究者
Yanhong Deng
professor
Sun Yat-sen University
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Unknown
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