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A single center, randomized controlled trial on the treatment of elderly patients with acute myeloid leukemia by attack and reinforcement combined with demethylatio

Phase 1
Conditions
elderly patients with acute myeloid leukemia
Registration Number
ITMCTR2000003828
Lead Sponsor
Yueyang integrated traditional Chinese and Western Medicine Hospital Affiliated to Shanghai University of traditional Chinese Medicine
Brief Summary

Not available

Detailed Description

Not available

Recruitment & Eligibility

Status
Pending
Sex
All
Target Recruitment
Not specified
Inclusion Criteria

1. Meet the diagnostic criteria of Western medicine for senile AML;
2. Accord with the diagnostic criteria of TCM syndrome of senile AML;
3. Aged 60 to 80 years old;
4. The patients with an estimated survival time of more than 3 months;
5. Willing to accept the treatment of this program and sign the informed consent.

Exclusion Criteria

1. Acute promyelocytic leukemia;
2. Patients with serious organic diseases such as heart, brain, liver and kidney, and patients with other malignant tumors and mental diseases;
3. Coexisting diseases with any significant abnormalities or poor nutritional status, which affect the life safety and compliance of patients;
4. Allergy to any drug involved in the scheme;
5. Participate in other clinical researchers one month before enrollment.

Study & Design

Study Type
Interventional study
Study Design
Not specified
Primary Outcome Measures
NameTimeMethod
overall remission rate;
Secondary Outcome Measures
NameTimeMethod
RD level of bone marrow;Complete remission rate;Quality of life assessment;Quantitative score of TCM Syndromes;
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