Picoprep versus Moviprep.

Completed

Conditions: colonoscopy, colon cancer screening, bowel preparationcoloscopie, darmkanker screening, darmvoorbereiding

Registration Number: NL-OMON23520

Lead Sponsor: Academic Medical Centre, University of Amsterdam

Brief Summary: Mathus-Vliegen EM, Kemble UM. A prospective randomized blinded comparison of sodium phosphate and polyethylene glycol-electrolyte solution for safe bowel cleansing. Aliment Pharmacol Ther 2006;23:543-52.

Detailed Description: Not available

Recruitment & Eligibility

Status: Completed

Sex: Not specified

Target Recruitment: 340

Inclusion Criteria

Outpatients, older than 18 years, with an indication to undergo colonoscopy, who can give informed consent and who are able to have bowel cleansing at home.

Exclusion Criteria

Patients with significant gastroparesis or gastric outlet obstruction; ileus; known or suspected bowel obstruction or perforation; severe chronic renal failure (creatinine clearance < 30mL/minute); severe congestive heart failure (AHA class III or IV); toxic colitis or megacolon; pregnant patients or patients giving breastfeeds.
Patients with a subtotal colectomy or a colostomy will be excluded because of insufficient remaining colonic surface to evaluate the effects of bowel cleansing.

Study & Design

Study Type: Interventional

Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
The primary outcome is the achievement of a good cleansing (Ottawa) score, and quality standards such as the caecal intubation rate, intubation and withdrawal time, polyp detection rate and complications.

Secondary Outcome Measures

Name	Time	Method
Preparation tolerance; preparation safety; comparison of the 3 available bowel preparation assessment scales.<br /><br>Confounders influencing the main outcome and secondary endpoints may be age, gender, the starting time of colonoscopy, BMI, colonic disease (IBD, diverticulosis, stenosis, obstruction, constipation), the presence of disease (diabetes, cirrhosis, CVA, dementia, anemia) and the use medication (calcium channel blockers, tricyclic antidepressants) are studies as well.