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Clinical Trials/NCT00390663
NCT00390663
Unknown
Phase 4

A Prospective Randomised Controlled Trial of Management of Recurrent Nosebleeds in Children: Antiseptic Cream Alone v's Antiseptic Cream With Nasal Cautery

NHS Greater Glasgow Yorkhill Division1 site in 1 country216 target enrollmentStarted: October 2006Last updated:
ConditionsEpistaxis

Overview

Phase
Phase 4
Sponsor
NHS Greater Glasgow Yorkhill Division
Enrollment
216
Locations
1

Overview

Brief Summary

To determine whether the selective application of a combined treatment regimen of silver nitrate cautery and 4 weeks of Naseptin cream is superior to naseptin treatment alone in the management of recurrent paediatric epistaxis.

Study Design

Study Type
Interventional
Allocation
Randomized
Intervention Model
Single Group
Primary Purpose
Treatment
Masking
Double

Eligibility Criteria

Ages
1 Year to 14 Years (Child)
Sex
All
Accepts Healthy Volunteers
No

Inclusion Criteria

  • Children aged 1 - 14
  • History of repeated epistaxis with at least 1 episode in the previous 4 weeks prior to attending the ENT clinic.
  • Presence of prominent vessels on the anterior nasal septum on the side that reportedly bleeds (or on at least one side if bleeding is reported to be bilateral)

Exclusion Criteria

  • No prominent vessels on examination (these children will be randomised but will be prescribed Naseptin alone and followed up in the same way as the children in the trial, for completeness of data)
  • Known bleeding disorders.
  • Allergy to peanuts, neomycin or chlorhexidine
  • Other causes of nose bleeding eg tumour.

Investigators

Sponsor
NHS Greater Glasgow Yorkhill Division
Sponsor Class
Other

Study Sites (1)

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