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The Experiences of Patients Living With Malignant Pleural Effusions

Conditions
Malignant Pleural Effusion
Registration Number
NCT03235999
Lead Sponsor
Gloucestershire Hospitals NHS Foundation Trust
Brief Summary

Up to 20 patients with malignant pleural effusions will be interviewed about their experiences of having this condition and its management.

Detailed Description

Not available

Recruitment & Eligibility

Status
UNKNOWN
Sex
All
Target Recruitment
20
Inclusion Criteria
  1. Adults diagnosed with a malignant pleural effusion
  2. Has undergone either talc pleurodesis or IPC
  3. Have signed a consent form prior to entering the study
  4. Life expectancy > 6 weeks based on LENT guidelines (Low/Moderate risk group) - The LENT score calculation assigns 0 (<1500 IU/L) or 1 (>1500 IU/L) for pleural fluid LDH level; 0 to 3 points for matching ECOG performance scores (3 and 4 are combined); 0 (<9) or 1 (>9) for neutrophil-to-lymphocyte ratio; and 0 (lowest risk), 1 (moderate risk), or 3 (highest risk) for tumor type.
Exclusion Criteria
  1. Any patient who is unable to understand sufficient English to take part in the semi-structured interviews
  2. Weakness or fatigue sufficient so that the patient is unable to take part in the interviews

Study & Design

Study Type
OBSERVATIONAL
Study Design
Not specified
Primary Outcome Measures
NameTimeMethod
Patient Experiences of living with malignant pleural effusion and different pleural procedures4 weeks after IPC placement or talc pleurodesis

Qualitative interviews - Interviews will be recorded on a digital audio recorder and then downloaded on to a password protected computer. The interviews will then be sent for transcription using secure email and anonymised.

We will perform thematic analysis on the interview data. This is a process to help explore the experiences of the subject as they describe it rather than looking at how they talk about the experience. Themes will be drawn from the data following coding. Common codes relating to a theme, for example pain, will be identified and examples of text used to demonstrate the theme extracted. This will ensure a wide variety of quotes across the interviews rather than focusing on one main or a subset of interviews. We will use an inductive approach whereby themes will emerge and not be developed in advance. Emerging codes will be checked by the supervisory team.

There will be no numerical, quantitative data for analysis.

Secondary Outcome Measures
NameTimeMethod

Trial Locations

Locations (1)

Gloucestershire Hospitals NHS Foundation Trust

🇬🇧

Cheltenham, Gloucestershire, United Kingdom

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