MedPath

Single-stage ERCP and Laparoscopic Cholecystectomy for Cholecystocholedocholithiasis: Which to Start With?

Completed
Conditions
Choledocholithiasis With Cholecystitis
Biliary Stones
Registration Number
NCT06340594
Lead Sponsor
Assiut University
Brief Summary

Chronic calculous cholecystitis is associated with common bile duct (CBD) stones in approximately 12% of patients. These patients need both cholecystectomy and CBD clearance of stones. The standard for cholecystectomy is laparoscopic cholecystectomy (LC) and the mostly common treatment used for CBD clearance is Endoscopic Retrograde Cholangiopancreatography (ERCP). The two interventions can be combined to be done at the same time under single anesthesia session. Studies of single stage ERCP+LC showed confirmed the safety and efficacy of the combined technique. However, some surgeons start with the ERCP while others start with LC.The aim of this study is to compare the start with ERCP followed by LC to the start with LC followed by ERCP when the two techniques are combined at the same session for treatment of chronic calculous cholecystitis associated with CBD stones regarding efficacy and safety of the two approaches.

Detailed Description

Not available

Recruitment & Eligibility

Status
COMPLETED
Sex
All
Target Recruitment
115
Inclusion Criteria
  • Patients underwent single stage ERCP+LC for cholecystocholedocholithiasis
Exclusion Criteria
  • Contraindications to ERCP, or laparoscopic surgery
  • Cholangitis and pancreatitis
  • Previously failed ERCP

Study & Design

Study Type
OBSERVATIONAL
Study Design
Not specified
Primary Outcome Measures
NameTimeMethod
Operative time operative timetime in minutes from intubation of the patient to the end of procedure

total operative time of both ERCP+LC

Secondary Outcome Measures
NameTimeMethod
Mortality rateup to 1 month postoperative

number of deaths intraoperative and postoperative related to surgery

CBD clearance rateup to 2 years

success rate of retrieval of stones

Length of hospital stayup to 2 weeks post-operative

days of hospital stay

Trial Locations

Locations (1)

Faculty of Medicine-Assiut University -Assiut-Egypt

🇪🇬

Assiut, Asyut, Egypt

Faculty of Medicine-Assiut University -Assiut-Egypt
🇪🇬Assiut, Asyut, Egypt

MedPath

Empowering clinical research with data-driven insights and AI-powered tools.

© 2025 MedPath, Inc. All rights reserved.