Effect of Ingudi Paste and Jatiphala Paste in Vyanga (Melasma)
- Conditions
- Disorder of pigmentation, unspecified. Ayurveda Condition: VYANGAH, (2) ICD-10 Condition: L819||Disorder of pigmentation, unspecified. Ayurveda Condition: VYANGAH,
- Registration Number
- CTRI/2021/05/033443
- Lead Sponsor
- National Institute of Ayurveda
- Brief Summary
Introduction: -Skin diseases and its’ adverse effects on appearance and personality had been explained by Acharya Sushruta as kshudra rogas for the first time among the Ayurveda amenities. Among those kshudra rogas vyanga is considered as a common skin disorder found in present period. Almost all Acharyas have considered vyanga as a kshudra roga except, Acarya Charaka;
he mentions vyanga under raktadhatugata vikara.1 Acharya Sushruta also mention vyanga under raktadhatugata vikara.2
According to Ayurveda concepts, it is manifested due to vitiation of vata and pitta dosha. These doshas vitiated by krodha, aayaas, ushna, tikshna, ruksha dietary habits. Thereby, it results to presence of niruja, tanu, and shyava varna yukta mandala on Mukha pradesh.
Vyanga is a common disorder affecting the face area and can be an embarrassing condition. According to the appearance of vyanga, the disease ‘melasma’ can be correlated. In these both conditions, the patches of hyper pigmentation are seen especially on cheeks, nose, forehead and chin.
In this research, significance is to know the efficacy of the Ingudi (Balanites aegyptiaca, Linn.Delile) phal majja lepa which mentioned in Rajmartand, which describes Ingudi fruit pulp lepa with water to cure diseases of face Vyanga (Melasma)4 and Jatiphala (Myristica fragrans,Houtt.) seed lepa is mentioned in Chakardatta Chikitsa which describes Jatiphala lepa with water cure Nilli and Vyanga.
Need of Study: - Jathipala is being used by the people in many skin disorders for a long time. Alternatively, there are many references of Ingudi are also available in classics in relation to skin disorders and easily available. Hence, this clinical study will be taken to compare the effect of Ingudi lepa and Jatiphala lepa on Vaynga to provide a safe, cost effective treatment.
Hypothesis
Null Hypothesis Ho:
There is no difference between the Ingudi lepa and Jatiphala Lepa in the Melasma Area and Severity Index (MASI).
Primary outcome: Reduction in Melasma Area and Severity Index (MASI).
Secondary outcome: Changes in skin colour .
MATERIAL AND METHOD:-
Conceptual study-
Drug Review- Critical review of the trial drugs will be done in the research work under Vyanga. Ingudi phal majja (mesocarp) (Balanites aegyptica, Linn.Delile) commonly known as Hingot in Hindi and Jatiphala (Myristica fragrans,Houtt.) beeja (seed )commonly known as Nutmeg in English will be elaborated under drug review.
Outcomes of The Study: -
Primary outcome: Reduction in Melasma Area and Severity Index (MASI).
Secondary outcome: Changes in skin colour .
Assessment criteria:
1. Photograph will be taken before the treatment and after the treatment in day light from same distance.
2. Melasma Area and Severity Index (MASI).
All data observed will be recorded. The study area of patients will be digitally photograph on each observation day and recorded. In these, findings prior and after the treatment will be compared and statistically analyzed for their significance to draw conclusion.
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Not Yet Recruiting
- Sex
- All
- Target Recruitment
- 30
- Patients presenting Vyanga as clinical features according to Susruta Samhita. 2. Patients of either sex. 3. Patients of age between 18.
- Melasma due to tubercular therapy or malignant cases.
- Patients having diagnosis of major illness like IHD, HTN, MI, TB, COPD, DM etc.
- would be excluded from trial.
- Diagnosed patients of Carcinoma, Burns, Herpes, Eczema, Psoriasis, Measles, Chickenpox, Leucoderma and Leprosy.
- Person suffering from any infective or contagious skin disease or under medication with antibiotics, antifungal and steroid.
- Patients of uncontrolled hormonal disease.
- Any kind of hereditary skin disorder 8.
- With present history of pregnancy and chronic constipation.
- Patient suffering from Melasma more than five year.
- Patients who are reporting allergy history of trail drugs.
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Reduction in Melasma Area and Severity Index (MASI). in one month ( 4 week)treatment Reduction in Melasma Area and Severity Index (MASI). in one month ( 4 week) treatment
- Secondary Outcome Measures
Name Time Method Changes in face skin colour in 4 weeks
Trial Locations
- Locations (1)
opd no19 dravyaguna department arogya shalla hospital nia jaipur
🇮🇳Jaipur, RAJASTHAN, India
opd no19 dravyaguna department arogya shalla hospital nia jaipur🇮🇳Jaipur, RAJASTHAN, IndiaDr bhawani singh rathorePrincipal investigator9414229977bhawani.dr.rathore@gmail.com