ACTRN12620000031965进行中（未招募）3 期
Melatonin to Improve Sleep in Patients Undergoing Major Abdominal Surgery:A Double-blind, Randomised Placebo-controlled Trial
Hunter New England Local Health District.0 个研究点目标入组 152 人开始时间: 2020年1月20日最近更新:
试验速览
- 阶段
- 3 期
- 状态
- 进行中（未招募）
- 发起方
- 入组人数
- 152
研究概览
简要总结
暂无简介。
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomised controlled trial
- 主要目的
- Treatment
- 盲法
- Blinded (masking used)
入排标准
- 年龄范围
- 18 Years 至 o limit（—）
- 性别
- All
入选标准
- •All English-speaking patients 18 years and over undergoing elective/semi-elective major abdominal surgery with an anticipated length of stay greater than 48 hours.
排除标准
- •Patients from the above group will be excluded if they:
- •Are unable to give written informed consent to take part in the study,
- •Patients who require the use of a trained healthcare interpreter to be able to understand study information.
- •Lack decision-making capacity,
- •Expected stay less than 48 hours,
- •Concurrent use of benzodiazepine, non-benzodiazepine (Z-drugs) or melatonin,
- •Alcohol consumption > 13 units/week for women and >20 units/week for men.
- •Currently taking melatonin
- •Drug interaction with melatonin.
- •Allergy to melatonin or its excipients (may contain lactose)
- •Decreased renal function as defined by an eGFR of <30 mL/min/1.73m2
- •Decreased liver function defined as an AST > 500 U/L or ALT >500 U/L
- •Pregnant or breastfeeding females
- •Enrolment in other clinical trials involving an investigational agent
- •Taking quinolones, carbamazepine and rifampicin, fluvoxamine, 5- or 8- methoxypsoralen, cimetidine, oestrogens.
研究者
相似试验
已完成
2 期
The effect of melatonin treatment in patients with Irritable Bowel SyndromeIrritabale Bowel Syndrome.Irritable bowel syndrome with diarrhoea, Irritable bowel syndrome without diarrhoeaK58.9, k58IRCT2017012532186N1Vice chancellor for research, Arak University of Medical Sciences64
已完成
3 期
Melatonin and Strokeischemic brain stroke.Cerebral infarctionIRCT2015012917811N6Arak University of Medical Sciences , Office of Vice Chancellor for Research58
招募中
2 期
Efficacy of melatonin as an adjunct in the treatment of acute maniaBipolar Disorder.Mania episodeIRCT201705181556N98Tehran University of Medical Sciences50
尚未招募
3 期
melatonin in patients with COVID-19U07.2COVID-19, virus not identifiedCOVID-19 disease.IRCT20200506047323N7Bandare-abbas University of Medical Sciences60
招募中
3 期
Efficacy of melatonin for the treatment of moderate to severe vincristine-induced neuropathy in pediatric malignanciesIRCT20200710048068N1Tehran University of Medical Sciences20