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Clinical Trials/NCT04787874
NCT04787874
Recruiting
Not Applicable

Effect of Health Habits on Outcomes in Plastic and Reconstructive Surgery

Stanford University2 sites in 1 country520 target enrollmentJune 21, 2021

Overview

Phase
Not Applicable
Intervention
Not specified
Conditions
Ventral Hernia
Sponsor
Stanford University
Enrollment
520
Locations
2
Primary Endpoint
Patient-Reported Outcome Measures: Abdominal Surgery Impact Scale (ASIS) on Post-op days 7-14
Status
Recruiting
Last Updated
4 years ago

Overview

Brief Summary

The purpose of this study is to determine whether a program to optimize patient physical fitness and nutrition ("prehabilitation") prior to and after plastic surgery involving the abdomen improves surgical outcomes. The investigators hope to determine how a multimodal peri-operative prehabilitation program can be most effective in engaging and motivating patients to physically and mentally get ready for an abdominally-based plastic surgery operation. The overall goal is to determine if this program will improve post-operative recovery after abdominally-based plastic surgery. The importance of this new knowledge is better understanding of ways that plastic surgeons can improve outcomes, engagement, and experience of patients undergoing abdominally-based plastic surgery operations. This would translate to increased healthcare value and better long-term outcomes.

Registry
clinicaltrials.gov
Start Date
June 21, 2021
End Date
June 2, 2025
Last Updated
4 years ago
Study Type
Interventional
Study Design
Parallel
Sex
All

Investigators

Responsible Party
Principal Investigator
Principal Investigator

Cara Black

Resident Physician, PGY-1

Stanford University

Eligibility Criteria

Inclusion Criteria

  • Adult patients (\>18 years) who are undergoing elective abdominally-based plastic surgery operations in 3+ weeks by one of the following plastic surgeons: Nazerali, Lee, Murphy, Nguyen, Lorenz.

Exclusion Criteria

  • Patients who do not speak English
  • Patients who do not have access to a smartphone or internet/cell service.
  • Patients who are undergoing another intervention study that consists of a nutrition and/or exercise behavior change.

Outcomes

Primary Outcomes

Patient-Reported Outcome Measures: Abdominal Surgery Impact Scale (ASIS) on Post-op days 7-14

Time Frame: Post-operative days 7-14

Will use the Abdominal Surgery Impact Scale (ASIS) to assess the patient's perceived health following their surgical procedure. The ASIS score ranges from 18-126, having higher scores indicate better quality of life.

Patient-Reported Outcome Measures: RAND 36-Item Health Survey (RAND-36) on Post-op day 30

Time Frame: Post-operative day 30

Will use the RAND 36-Item Health Survey (RAND-36) to assess the patient's perceived health following their surgical procedure. The score for RAND-36 ranges from 0-100, having higher scores mean better outcomes.

Patient-Reported Outcome Measures: Abdominal Surgery Impact Scale (ASIS) on Post-op day 30

Time Frame: Post-operative day 30

Will use the Abdominal Surgery Impact Scale (ASIS) to assess the patient's perceived health following their surgical procedure. The ASIS score ranges from 18-126, having higher scores indicate better quality of life.

Occurrence of surgical complications (Post-op days 7-14)

Time Frame: Post-operative days 7-14

Will analyze the occurrence of surgical complications after surgery. Hematoma, seroma, or abscess.

Occurrence of surgical complications (Post-op day 30)

Time Frame: Post-operative day 30

Will analyze the occurrence of surgical complications after surgery. Hematoma, seroma, or abscess.

Occurrence of surgical complications (Post-op day 90)

Time Frame: Post-operative day 90

Will analyze the occurrence of surgical complications after surgery. Hematoma, seroma, or abscess.

Occurrence of surgical complications (Post-op day 180)

Time Frame: Post-operative day 180

Will analyze the occurrence of surgical complications after surgery. Hematoma, seroma, or abscess.

Occurrence of surgical complications (Post-op day 360)

Time Frame: Post-operative day 360

Will analyze the occurrence of surgical complications after surgery. Hematoma, seroma, or abscess.

Patient-Reported Outcome Measures: RAND 36-Item Health Survey (RAND-36) on Post-op days 7-14

Time Frame: Post-operative days 7-14

Will use the RAND 36-Item Health Survey (RAND-36) to assess the patient's perceived health following their surgical procedure. The score for RAND-36 ranges from 0-100, having higher scores mean better outcomes.

Patient-Reported Outcome Measures: RAND 36-Item Health Survey (RAND-36) on Post-op day 90

Time Frame: Post-operative day 90

Will use the RAND 36-Item Health Survey (RAND-36) to assess the patient's perceived health following their surgical procedure. The score for RAND-36 ranges from 0-100, having higher scores mean better outcomes.

Patient-Reported Outcome Measures: Abdominal Surgery Impact Scale (ASIS) on Post-op day 90

Time Frame: Post-operative day 90

Will use the Abdominal Surgery Impact Scale (ASIS) to assess the patient's perceived health following their surgical procedure. The ASIS score ranges from 18-126, having higher scores indicate better quality of life.

Patient-Reported Outcome Measures: RAND 36-Item Health Survey (RAND-36) on Post-op day 180

Time Frame: Post-operative day 180

Will use the RAND 36-Item Health Survey (RAND-36) to assess the patient's perceived health following their surgical procedure. The score for RAND-36 ranges from 0-100, having higher scores mean better outcomes.

Patient-Reported Outcome Measures: Abdominal Surgery Impact Scale (ASIS) on Post-op day 180

Time Frame: Post-operative day 180

Will use the Abdominal Surgery Impact Scale (ASIS) to assess the patient's perceived health following their surgical procedure. The ASIS score ranges from 18-126, having higher scores indicate better quality of life.

Physical Function Test: 5-times-sit-to-stand test on Post-op Day 90

Time Frame: Post-operative day 90

Will use the 5-times-sit-to-stand test. The 5-times-sit-to-stand test is a method to quantify functional lower extremity strength. Lower times indicate better scores.

Patient-Reported Outcome Measures: RAND 36-Item Health Survey (RAND-36) on Post-op day 360

Time Frame: Post-operative day 360

Will use the RAND 36-Item Health Survey (RAND-36) to assess the patient's perceived health following their surgical procedure. The score for RAND-36 ranges from 0-100, having higher scores mean better outcomes.

Patient-Reported Outcome Measures: Abdominal Surgery Impact Scale (ASIS) on Post-op day 360

Time Frame: Post-operative day 360

Will use the Abdominal Surgery Impact Scale (ASIS) to assess the patient's perceived health following their surgical procedure. The ASIS score ranges from 18-126, having higher scores indicate better quality of life.

Physical Function Test: 6-minute walk test at Time of Enrollment

Time Frame: Time of enrollment

Will use the 6-minute walk test. The 6-minute walk test will be used to assess aerobic capacity and endurance. A normal walk distance ranges from 400 to 700 m.

Physical Function Test: 5-times-sit-to-stand test at Time of Enrollment

Time Frame: Time of enrollment

Will use the 5-times-sit-to-stand test. The 5-times-sit-to-stand test is a method to quantify functional lower extremity strength. Lower times indicate better scores.

Physical Function Test: Timed-up-and-go test at Time of Enrollment

Time Frame: Time of enrollment

Will use the timed-up-and-go test. The timed-up-and go test assesses one's mobility. A lower score signifies better mobility.

Physical Function Test: 6-minute walk test at 3 weeks

Time Frame: 3 weeks

Will use the 6-minute walk test. The 6-minute walk test will be used to assess aerobic capacity and endurance. A normal walk distance ranges from 400 to 700 m.

Physical Function Test: 5-times-sit-to-stand test at 3 weeks

Time Frame: 3 weeks

Will use the 5-times-sit-to-stand test. The 5-times-sit-to-stand test is a method to quantify functional lower extremity strength. Lower times indicate better scores.

Physical Function Test: Timed-up-and-go test at 3 weeks

Time Frame: 3 weeks

Will use the timed-up-and-go test. The timed-up-and go test assesses one's mobility. A lower score signifies better mobility.

Physical Function Test: 6-minute walk test on Post-op Day 30

Time Frame: Post-operative day 30

Will use the 6-minute walk test. The 6-minute walk test will be used to assess aerobic capacity and endurance. A normal walk distance ranges from 400 to 700 m.

Physical Function Test: 5-times-sit-to-stand-test on Post-op Day 30

Time Frame: Post-operative day 30

Will use the 5-times-sit-to-stand test. The 5-times-sit-to-stand test is a method to quantify functional lower extremity strength. Lower times indicate better scores.

Physical Function Test: Timed-up-and-go test on Post-op Day 30

Time Frame: Post-operative day 30

Will use the timed-up-and-go test. The timed-up-and go test assesses one's mobility. A lower score signifies better mobility.

Physical Function Test: 6-minute walk test on Post-op Day 90

Time Frame: Post-operative day 90

Will use the 6-minute walk test. The 6-minute walk test will be used to assess aerobic capacity and endurance. A normal walk distance ranges from 400 to 700 m.

Physical Function Test: Timed-up-and-go test on Post-op Day 90

Time Frame: Post-operative day 90

Will use the timed-up-and-go test. The timed-up-and go test assesses one's mobility. A lower score signifies better mobility.

Secondary Outcomes

  • Change from Baseline Albumin Levels at Time of Surgery(Enrollment to time of surgery)
  • Change from Baseline Prealbumin Levels at Time of Surgery(Enrollment to time of surgery)
  • Change from Baseline Transferrin Levels at Time of Surgery(Enrollment to time of surgery)
  • Change from Baseline C-reactive Protein Levels at Time of Surgery(Enrollment to time of surgery)
  • Change from Baseline Erythrocyte Sedimentation Rates at Time of Surgery(Enrollment to time of surgery)
  • Change from Baseline Hemoglobin A1C Levels at Time of Surgery(Enrollment to time of surgery)
  • Change from Baseline Plasma Glucose Levels at Time of Surgery(Enrollment to time of surgery)
  • Change from Baseline White Blood Cell Count at Time of Surgery(Enrollment to time of surgery)
  • Change from Baseline Hemoglobin Levels at Time of Surgery(Enrollment to time of surgery)
  • Change from Baseline Hematocrit Levels at Time of Surgery(Enrollment to time of surgery)
  • Change from Baseline Platelet Levels at Time of Surgery(Enrollment to time of surgery)
  • Change from Baseline Chloride Levels at Time of Surgery(Enrollment to time of surgery)
  • Change from Baseline Sodium Levels at Time of Surgery(Enrollment to time of surgery)
  • Change from Baseline Potassium Levels at Time of Surgery(Enrollment to time of surgery)
  • Change from Baseline Carbon Dioxide Levels at Time of Surgery(Enrollment to time of surgery)
  • Change from Baseline Blood Urea Nitrogen Levels at Time of Surgery(Enrollment to time of surgery)
  • Change from Baseline Creatinine Levels at Time of Surgery(Enrollment to time of surgery)
  • Change from Baseline Blood Glucose Levels at Time of Surgery(Enrollment to time of surgery)

Study Sites (2)

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