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CT-322 in Treating Patients With Advanced Solid Tumors and Non-Hodgkin's Lymphoma

Phase 1
Completed
Conditions
Cancer
Registration Number
NCT00374179
Lead Sponsor
Adnexus, A Bristol-Myers Squibb R&D Company
Brief Summary

RATIONALE: CT-322 may stop the growth of solid tumors or non-Hodgkin's lymphoma by stopping blood flow to the cancer.

PURPOSE: This phase I trial is studying the side effects of CT-322 in treating patients with advanced solid tumors or non-Hodgkin's lymphoma.

Detailed Description

Not available

Recruitment & Eligibility

Status
COMPLETED
Sex
All
Target Recruitment
40
Inclusion Criteria

Not provided

Exclusion Criteria

Not provided

Study & Design

Study Type
INTERVENTIONAL
Study Design
SINGLE_GROUP
Primary Outcome Measures
NameTimeMethod
Safety and tolerability of CT-322Throughout the study
Secondary Outcome Measures
NameTimeMethod
To evaluate the pharmacokinetics of CT-322 in these patients;Throughout the study
to assess whether antibodies to this drug develop in these patients; andThroughout the study
to make a preliminary assessment of the biological activity of CT-322 to alter tumor growth.Throughout the study

Trial Locations

Locations (3)

Indiana University Cancer Center

🇺🇸

Indianapolis, Indiana, United States

South Texas Accelerated Research Therapeutics

🇺🇸

San Antonio, Texas, United States

Institute for Drug Development

🇺🇸

San Antonio, Texas, United States

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