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CT-322 in Treating Patients With Advanced Solid Tumors and Non-Hodgkin's Lymphoma

Phase 1
Completed
Conditions
Cancer
Registration Number
NCT00374179
Lead Sponsor
Adnexus, A Bristol-Myers Squibb R&D Company
Brief Summary

RATIONALE: CT-322 may stop the growth of solid tumors or non-Hodgkin's lymphoma by stopping blood flow to the cancer.

PURPOSE: This phase I trial is studying the side effects of CT-322 in treating patients with advanced solid tumors or non-Hodgkin's lymphoma.

Detailed Description

Not available

Recruitment & Eligibility

Status
COMPLETED
Sex
All
Target Recruitment
40
Inclusion Criteria

Not provided

Exclusion Criteria

Not provided

Study & Design

Study Type
INTERVENTIONAL
Study Design
SINGLE_GROUP
Primary Outcome Measures
NameTimeMethod
Safety and tolerability of CT-322Throughout the study
Secondary Outcome Measures
NameTimeMethod
To evaluate the pharmacokinetics of CT-322 in these patients;Throughout the study
to assess whether antibodies to this drug develop in these patients; andThroughout the study
to make a preliminary assessment of the biological activity of CT-322 to alter tumor growth.Throughout the study

Trial Locations

Locations (3)

Indiana University Cancer Center

πŸ‡ΊπŸ‡Έ

Indianapolis, Indiana, United States

South Texas Accelerated Research Therapeutics

πŸ‡ΊπŸ‡Έ

San Antonio, Texas, United States

Institute for Drug Development

πŸ‡ΊπŸ‡Έ

San Antonio, Texas, United States

Indiana University Cancer Center
πŸ‡ΊπŸ‡ΈIndianapolis, Indiana, United States

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