Evaluation of phytopharmaceuticals to improve the prognosis of Covid-19 disease in Togo.
Phase 2
Recruiting
- Conditions
- SARS-CoV-2 Infection
- Registration Number
- PACTR202009483194545
- Lead Sponsor
- niversity of Lome
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Recruiting
- Sex
- All
- Target Recruitment
- 250
Inclusion Criteria
Patients over 18 years of age.
- Infected with a Covid-19 infection confirmed by a specific PCR.
- Hospitalized.
- Fever or cough
- No signs of respiratory distress
- Naïve of specific treatment for Covid-19.
- Informed consent signed by the patient.
Exclusion Criteria
- Renal insufficiency (eGFR <30 ml/min, CKD-EPI formula).
- AST or ALT > 3 times normal
- Cirrhosis (stage = Child-Pugh B).
- Pregnancy or breastfeeding.
- Dementia or any other condition that does not allow for informed consent.
- Any reason that, at the discretion of the investigator, would compromise patient safety and cooperation in the trial.
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Proportion of patients with undetectable viral load
- Secondary Outcome Measures
Name Time Method Proportion of patients with clinical improvement on the 7-point ordinal scale ;Proportion of patients who died or were affected by respiratory distress syndrome;Prevalence of grade 3 and 4 adverse events in each treatment group ;Proportion of patient cured