Comparison of Norepinephrine infusion and bolus regimens in treatment of spinal induced hypotension during Cesarean delivery
Phase 3
- Conditions
- Health Condition 1: O00-O9A- Pregnancy, childbirth and the puerperium
- Registration Number
- CTRI/2019/08/020849
- Lead Sponsor
- Amrita Institute of Medical Sciences
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Open to Recruitment
- Sex
- Not specified
- Target Recruitment
- 0
Inclusion Criteria
1.Elective CS under spinal anaesthesia
2.Normal singleton pregnancy beyond 36
weeks gestation
3.ASA physical status 1 or 2
4. Weight 50-100 kg
5.Height 150-180 cm
Exclusion Criteria
1.Allergy or hypersensitivity to norepinephrine
2.Any hypertensive disorders of pregnancy
3.Cardiovascular or cerebrovascular disease
4.Fetal abnormalities
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method To compare the total dose of norepinephrine required to maintain maternal blood pressure when used as bolus or infusion in patients undergoing caesarean section under spinal anaesthesia.Timepoint: intraoperative period
- Secondary Outcome Measures
Name Time Method To compare the effects of bolus versus infusion of norepinephrine on incidence of bradycardia, hypertension ,nausea and vomiting in mother and foetal outcomes as assessed by APGAR score and umbilical vein pH.Timepoint: intraoperative period