Cinacalcet for the treatment of hypercalcemia with persistent hyperparathyroidism in renal transplant recipients: a case siries study.

Not Applicable

• Conditions: Hypercalcemia with persistent hyperparathyroidism in renal transplant recipients.

• Registration Number: JPRN-UMIN000003236
• Lead Sponsor: St Marianna University

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Results First Posted: 1900-01-01
• Study Start: 2010-02-26
• Study Completion: 2012-12-31
• Last Update Posted: 17 October 2023

Recruitment & Eligibility

• Status: Complete: follow-up complete
• Sex: All
• Target Recruitment: 15

Inclusion Criteria

Not provided

Exclusion Criteria

1.age below 20 years old or pregnant 2.those who cannot agree to the study 3.inappropriate patients judged by primary or study physicians. 4.history of allergy or severe side effects by cinacalcet 5.those with severe liver dysfunction 6.concomitant use of vitamin D sterols, phosphate binder, calcium supplementation, bisphosphonates within 2 weeks before start of the study 7.history of parathyroidectomy or percutaneous ethanol injection therapy to parathyroid glands.

Study & Design

• Study Type: Interventional
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Absolute or relative changes in serum calcium, phosphate and intact-PTH levels.

Secondary Outcome Measures

Name	Time	Method
Absolute or relative changes of parathyroid grands size, bone density, vascular stiffness and bone metabolism markers (vitamin D, FGF23) and safety evaluations (by kidney function, interaction with immunosuppressives)