NCT06172426已完成不适用
Incidence of Psoriatic Arthritis Among Psoriasis Patients Newly Initiated With Secukinumab in a US Claims Database and a UK Registry
适应症
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 入组人数
- 1,171
- 试验地点
- 1
- 主要终点
- Exposure-adjusted incidence rate of PsA per 100 patient-years among PsO patients who newly initiated secukinumab
研究概览
简要总结
This was a retrospective cohort study to assess the incidence rate of psoriatic arthritis (PsA) among psoriasis (PsO) patients newly initiated on secukinumab or any biologics/apremilast (small molecule). The analysis was performed in two databases, IBM® MarketScan® database: Commercial Claims and Encounters (CCAE) and Medicare Supplemental Beneficiaries (MDCR) from 01 January 2010 to 30 June 2021 and BADBIR from 01 January 2016 to 01 September 2021.
研究设计
- 研究类型
- Observational
- 观察模型
- Cohort
- 时间视角
- Retrospective
入排标准
- 年龄范围
- 18 Years 至 —（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- 未提供
排除标准
- 未提供
结局指标
主要结局
Exposure-adjusted incidence rate of PsA per 100 patient-years among PsO patients who newly initiated secukinumab
时间窗: Up to 11.5 years
次要结局
- Health Assessment Questionnaires - Disability Index (HAQ-DI)(Baseline)
- Ethnicity(Baseline)
- Height(Baseline)
- Prior treatments(Baseline)
- Psoriasis Area and Severity Index (PASI)(Baseline)
- Weight(Baseline)
- Body mass index (BMI)(Baseline)
- Comorbidities(Baseline)
- Time from secukinumab initiation to the first PsA diagnosis(Up to 11.5 years)
- Age(Baseline)
- Gender(Baseline)
- Region(Baseline)
- Insurance type(Baseline)
- Hard-to-treat locations(Baseline)
- Dermatology Life Quality Index (DLQI)(Baseline)
- Body Surface Area (BSA)(Baseline)
研究者
研究点 (1)
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